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ProteomicsIntronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing
Background: The presence of nuclear mitochondrial DNA (numtDNA) has been reported within several nuclear genomes. Next to mitochondrial protein coding genes, numtDNA sequences also encode for mitochondrial tRNA genes. However, the biological roles of numtDNA, remain elusive. Results: Employing in s...
ORGANISM(S): Homo sapiens (Human) 
2020-10-28 | PXD022204 | Pride
Intronic splicing enhancer (ise) Constitutive splicing Nimtrna Mitochondrial trna Numtdna Trna Splicing Alternative splicing Trna-lookalikes Splicing regulatory element 
UnknownClinical impact of large genomic explorations at diagnosis in 198 pediatric solid tumors: a monocentric study aiming practical feasibility of precision oncology.
Not available
S-EPMC11492794 | biostudies-literature
ProteomicsPredictive protein biomarker signatures and the corresponding transcriptional cell state changes in human lung fibrosis (Plasma)
Single cell genomics enables characterization of disease specific cell states, while improvements in mass spectrometry workflows bring the clinical use of body fluid proteomics within reach. However, the correspondence of peripheral protein signatures to changes in cell state in diseased organs is c...
ORGANISM(S): Homo sapiens (Human) 
2020-09-18 | PXD017210 | Pride
Data integration Proteomics Fibrosis Single cell rna-seq Systems medicine Biomarker 
ProteomicsPredictive protein biomarker signatures and the corresponding transcriptional cell state changes in human lung fibrosis
Single cell genomics enables characterization of disease specific cell states, while improvements in mass spectrometry workflows bring the clinical use of body fluid proteomics within sight. However, the correspondence of peripheral protein signatures with cell state changes in diseased organs is cu...
ORGANISM(S): Homo sapiens (Human) 
2020-09-18 | PXD017145 | Pride
Data integration Proteomics Fibrosis Single cell rna-seq Systems medicine Biomarker 
UnknownIntegrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers.
Not available
S-EPMC8033531 | biostudies-literature
UnknownClinical use and predictors of outcome in venoarterial extracorporeal membrane (VA ECMO): insights from VERGE (VA ECMO Registry of Germany).
Not available
S-EPMC12460512 | biostudies-literature
UnknownIntraoperative radiotherapy in elderly patients with breast cancer: long-term follow-up results of the prospective phase II trial TARGIT-E.
Not available
S-EPMC12690916 | biostudies-literature
UnknownAlbumin Replacement Therapy in Septic Shock: A Randomized Clinical Trial.
Not available
S-EPMC12921518 | biostudies-literature
UnknownFractionated radiotherapy adjuvant to surgery of WHO-2 meningioma with and without gross total resection: a multicenter, retrospective cohort study of 1,452 patients.
Not available
S-EPMC12886253 | biostudies-literature
UnknownDeep learning enhanced ALPS reveals genetic and environmental factors of brain glymphatic function.
Not available
S-EPMC12878677 | biostudies-literature
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