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TranscriptomicsOligonucleotide Array CGH Profiles of Breast Cancer Patients Treated with High Dose or Conventional Chemotherapy
DNA copy number profiles can identify patients with a defect in BRCA1 or BRCA2. We previously showed that patients with a BRCA1 like profile benefit from intensified alkylating chemotherapy (IA, 4 cycles 5-fluorouracyl (5FU), epirubicin, cyclophosphamide (C) + 1 cycle carboplatin, thiotepa and cycl...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-GEOD-50407 | biostudies-arrayexpress
TranscriptomicsMale breast cancer copy number profiles
Exploratory study of copy number profiles of male breast cancer patients. The experiment contains 75 male breast cancer samples, analysed on a 135K whole genome CGH array
ORGANISM(S): Homo sapiens 
2015-09-13 | E-GEOD-57087 | biostudies-arrayexpress
GenomicsA carrier-assisted ChIP-seq method for Estrogen Receptor-chromatin interactions from breast cancer core needle biopsy samples
The Estrogen Receptor alpha (ERa) is the key transcriptional regulator in luminal breast cancer and the main target for adjuvant treatment. Luminal gene signatures are dictated by the transcriptional capacities of ERa, which are a direct consequence of the receptors binding preference at specific si...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-MTAB-1534 | biostudies-arrayexpress
Transcriptomicsdocetaxel response predic Illumina
Using gene expression profiling of mammary tumors generated in a mouse model for BRCA1-associated breast cancer we have searched for markers that correlate with response to the anti-cancer drugs docetaxel or cisplatin. To validate the results, the analysis was done on 2 different platforms (39K Mous...
ORGANISM(S): Mus musculus 
2011-10-26 | E-MTAB-413 | biostudies-arrayexpress
Transcriptomicsdocetaxel response prediction MEEBO
Using gene expression profiling of mammary tumors generated in a mouse model for BRCA1-associated breast cancer we have searched for markers that correlate with response to the anti-cancer drugs docetaxel or cisplatin. To validate the results, the analysis was done on 2 different platforms (39K Mous...
ORGANISM(S): Mus musculus 
2011-10-26 | E-MTAB-415 | biostudies-arrayexpress
GenomicOncoArray: Prostate Cancer

Original description of the study: From ELLIPSE (linked to the PRACTICAL consortium), we contributed ~78,000 SNPs to the OncoArray. A large fraction of the content was derived from the GWAS meta-analyses in European ancestry populations (overall and aggressive disease; ~27K SNPs). We also ...

phs001391 | dbGaP
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