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TranscriptomicsChIP-Seq and RNA-Seq of mouse E12.5
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-07-22 | E-GEOD-82100 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle
RNA sequencing was performed on sorted populations of Lgr6-positive and Lgr6-negative keratinocytes from the interfollicular epidermis and the hair follicle/sebaceous gland, in order to determine the compartment-specific expression signatures of Lgr6+ progenitor cells.
ORGANISM(S): Mus musculus 
2015-10-22 | E-MTAB-3533 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of mouse cerebral cortex
We have applied a recently developed, highly accurate and sensitive single-cell RNA-seq method (STRT/C1) to perform a molecular census of two regions of the mouse cerebral cortex: the somatosensory cortex and hippocampus CA1. We isolated cells fresh from somatosensory cortex (S1) and hippocampus CA1...
ORGANISM(S): Mus musculus 
2015-02-20 | E-GEOD-60361 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of mouse E12.5 brain regions
Investigations into the roles for Pbx1 and its transcriptional network in dopaminergic neuron development and Parkinson's Disease Three samples each from dorsal midbrain, forebrain, hindbrain, Alar plate, and ventral midbrain
ORGANISM(S): Mus musculus 
2016-07-22 | E-GEOD-82099 | biostudies-arrayexpress
GenomicsChIP-Seq for Pbx1 in the mouse E12.5 ventral midbrain
Investigations into the roles for Pbx1 and its transcriptional network in dopaminergic neuron development and Parkinson's Disease One sample each for Pbx1, IgG, and input
ORGANISM(S): Mus musculus 
2016-07-22 | E-GEOD-82098 | biostudies-arrayexpress
TranscriptomicsQuantitative single-cell RNA-seq
Purpose: We applied cDNA molecule counting using unique molecular identifiers combined with high-throughput sequencing to study the transcriptome of individual mouse embryonic stem cells, with spike-in controls to monitor technical performance. We further examined transcriptional noise in the embryo...
ORGANISM(S): Mus musculus 
2013-12-20 | E-GEOD-46980 | biostudies-arrayexpress
TranscriptomicsRNA-Seq Analysis Reveals Different Dynamics of Differentiation of Human Dermis- and Adipose-derived Stromal Stem Cells
Background: Tissue regeneration and recovery in the adult body depends on self-renewal and differentiation of stem and progenitor cells. Mesenchymal stem cells (MSCs) that have the ability to differentiate into various cell types, have been isolated from the stromal fraction of virtually all t...
ORGANISM(S): Homo sapiens 
2012-06-27 | E-GEOD-37521 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptome analysis of secretagogin mRNA expressing cells from the mouse hypothalamic paraventricular nucleus
The molecular mechanism regulating phasic corticotropin-releasing hormone (CRH) release from parvocellular neurons (PVN) remains poorly understood. Here, we find a cohort of parvocellular cells interspersed with magnocellular PVN neurons expressing secretagogin. Single-cell transcriptome analysis co...
ORGANISM(S): Mus musculus 
2014-11-20 | E-GEOD-63093 | biostudies-arrayexpress
TranscriptomicsCharacterization of the single-cell (ES and MEF) transcriptional landscape by highly multiplex RNA-Seq
Our understanding of the development and maintenance of tissues has been greatly aided by large-scale gene expression analysis. However, tissues are invariably complex, and expression analysis of a tissue confounds the true expression patterns of its constitutent cell types. Here we describe a novel...
ORGANISM(S): Mus musculus 
2011-05-24 | E-GEOD-29087 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of single cells of the oligodendrocyte lineage from nine distinct regions of the anterior-posterior and dorsal-ventral axis of the mouse juvenile central nervous system
5069 transcriptomes of single oligodendrocyte cells from spinal cord, substantia nigra-ventral tegmental area, striatum, amygdala, hypothalamic nuclei, zona incerta, hippocampus, and somatosensory cortex of male and female mice between post-natal day 21 and 90. The study aimed at identifying diverse...
ORGANISM(S): Mus musculus 
2016-06-10 | E-GEOD-75330 | biostudies-arrayexpress
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