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TranscriptomicsTranscription profiling by array of human CD4+ T-lymphocytes infected with VSVG-pseudotyped HIV-1 viruses lacking Env, Vpr, and Nef
The high mutation rate of HIV is linked to the generation of viruses expressing proteins with altered function whose impact on disease progression is unknown. We investigated the effects of HIV-1 viruses lacking Env, Vpr and Nef on CD4+ T cell gene expression using high-density DNA microarray analys...
ORGANISM(S): Homo sapiens 
2008-10-26 | E-GEOD-12963 | biostudies-arrayexpress
TranscriptomicsExpression data from Hes1 conditional knock-out NOTCH1-induced leukemias
To formally address the biological activity of Hes1 in vivo, we tested the interaction between oncogenic NOTCH1 and acute Hes1 loss in a retroviral-transduction bone marrow transplantation model of NOTCH-induced T-ALL Forced expression of activated NOTCH1 in this model typically results in full leuk...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-65863 | biostudies-arrayexpress
TranscriptomicsExpression data from CUTLL1 cells infected with shHES1
To formally address the biological activity of HES1 in vitro, we measured the transcriptional effect of HES1 inactivation infectiing CUTLL1 leukemia cell lines with shHES1 HES1 knockdown triggered apoptosis in human T-ALL lymphoblasts. We show that HES1 inactivation induces programmed cell death in ...
ORGANISM(S): Homo sapiens 
2015-05-07 | E-GEOD-65872 | biostudies-arrayexpress
UnknownFirst direct evidence of lion hunting and the early use of a lion pelt by Neanderthals.
Not available
S-EPMC10570355 | biostudies-literature
UnknownTranscriptional Profiles of California Sea Lion Peripheral NK and CD+8 T Cells Reflect Ecological Regionalization and Infection by Oncogenic Viruses.
Not available
S-EPMC6422979 | biostudies-literature
UnknownComplete mitochondrial genome sequence of Asiatic lion (Panthera leo persica).
Not available
S-EPMC7800587 | biostudies-literature
UnknownSplice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells.
Not available
S-EPMC7997720 | biostudies-literature
UnknownTrial Watch: Adoptive TCR-Engineered T-Cell Immunotherapy for Acute Myeloid Leukemia.
Not available
S-EPMC8469736 | biostudies-literature
UnknownPleural mesothelioma in a California sea lion (Zalophus californianus).
Not available
S-EPMC10539812 | biostudies-literature
UnknownLytic efficiency of immunosuppressive drug-resistant armoured T cells against circulating HBV-related HCC in whole blood.
Not available
S-EPMC10460197 | biostudies-literature
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