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TranscriptomicsClassification of Myeloma Using Global MicroRNA Profiling
Myeloma is a heterogeneous disease. In this work we used global microRNA profiling to classify clinical samples from UK MRC Myeloma IX, and developed a microRNA-based M-bM-^@M-^\outcome classifierM-bM-^@M-^] for risk stratification. Global microRNA expression profiling was carried out in 163 newly d...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-41276 | biostudies-arrayexpress
TranscriptomicsSmall nucleolar RNAs and small Cajal body-specific RNAs show distinct transcriptional profiles in the context of the molecular heterogeneity of multiple myeloma.
Small nucleolar RNAs (snoRNAs) and small Cajal body-specific RNAs (scaRNAs) are non-coding RNAs involved in the maturation of other RNA molecules and generally located in the introns of host genes. It is now emerging that altered sno/scaRNAs expression may play a pathological role in cancer. This st...
ORGANISM(S): Homo sapiens 
2013-06-25 | E-GEOD-39683 | biostudies-arrayexpress
TranscriptomicsIntegrative genomic approach reveals expression of intronic miR-335, miR-342, and miR-561 in multiple myeloma
The role of microRNAs (miRNAs) in multiple myeloma (MM) has yet to be fully elucidated. To identify miRNAs that are potentially deregulated in MM, we investigated those mapping within transcription units, based on evidence that intronic miRNAs are frequently coexpressed with their host genes. To thi...
ORGANISM(S): Homo sapiens 
2008-11-10 | E-GEOD-11522 | biostudies-arrayexpress
TranscriptomicsIdentification of MicroRNA Expression Patterns and a MicroRNAs/mRNA Regulatory Network in Multiple Myeloma
To date, little evidence of miRNA expression/deregulation in multiple myeloma (MM) has been reported. To characterize miRNA expression profiling of MM plasma cells (PCs) and integrate miRNA expression data with other molecular features of MM patients, global miRNA expression profiles were generated ...
ORGANISM(S): Homo sapiens 
2010-06-21 | E-GEOD-17498 | biostudies-arrayexpress
UnknownHeterometallic triiron-oxo/hydroxo clusters: effect of redox-inactive metals.
Not available
S-EPMC3953215 | biostudies-literature
TranscriptomicsIntegrated genomics approach to detect allelic imbalances in multiple myeloma, SNP data
A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide dosage effect on gene and microRNA expression Multiple myeloma (MM) is characterized by marked genomic instability. Beyond structural rearrangements, a relevant...
ORGANISM(S): Homo sapiens 
2009-05-16 | E-GEOD-16121 | biostudies-arrayexpress
TranscriptomicsA SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma
A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide dosage effect on gene and microRNA expression This SuperSeries is composed of the following subset Series: GSE13591: Integrated genomics approach to detect alle...
ORGANISM(S): Homo sapiens 
2009-05-16 | E-GEOD-16122 | biostudies-arrayexpress
UnknownOats in the diet of children with celiac disease: preliminary results of a double-blind, randomized, placebo-controlled multicenter Italian study.
Not available
S-EPMC3847754 | biostudies-literature
UnknownRemote Oxidative Activation of a [Cp*Rh] Monohydride.
Not available
S-EPMC8891045 | biostudies-literature
TranscriptomicsAssessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias [Patient samples]
Multiple myeloma (MM) is a malignant disorder characterized by the clonal proliferation of plasma cells (PCs) in the bone marrow (BM). The genetic background and clinical course of the disease are largely heterogeneous, and MM pathophysiology ranges from the premalignant condition of monoclonal gamm...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-66291 | biostudies-arrayexpress
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