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GenomicsMycolicibacterium elephantis strain:Lipa
Mycolicibacterium elephantis strain:Lipa Genome sequencing and assembly
PRJNA282888 | ENA
GenomicsNo HCV-1 Subtype Misclassification by LiPA 2.0
No Genotype 1 Hepatitis C Virus (HCV) Subtype Misclassification by LiPA 2.0
PRJEB21943 | ENA
TranscriptomicsWhole genome expression profiling of rice leaves treated with Xanthomonas oryzae pv. oryzae secreted cell wall degrading lipase/esteraseA (LipA) at early time points, 30 min. and 120 min.
Treatment of rice tissues with purified preparations of a Xanthomonas oryzae pv. oryzae (Xoo) secreted plant cell wall degrading enzyme, Lipase/Esterase (LipA), elicits cell wall damage induced innate immune responses. LipA activity is required for induction of defense responses. In order to charact...
ORGANISM(S): Oryza sativa 
2015-06-30 | E-GEOD-53940 | biostudies-arrayexpress
GenomicsLipa regulates myeloid differentiation and is essential for intra-plaque macrophage accumulation during atherosclerosis
Lipa regulates myeloid differentiation and is essential for intra-plaque macrophage accumulation during atherosclerosis
PRJNA1142942 | ENA
TranscriptomicsTranscriptomic Characterization of LIPA+/+ and LIPA-/- iPSC-derived Macrophages
Using RNA-Seq, we examined the transcriptome profiles of human iPSC-derived macrophage (IPSDM) with knockout of the LIPA gene by CRISPR/Cas9 gene editing technologies.
ORGANISM(S): Homo sapiens 
2020-06-19 | GSE100260 | GEO
TranscriptomicsLipa regulates myeloid differentiation and is essential for intra-plaque macrophage accumulation during atherosclerosis
Lysosomal acid lipase (Lipa), which is primarily produced in the liver, has been identified as one of the earliest and most impactful genetic factors linked to human coronary artery diseases. Despite its original source, it is also found to be highly expressed in macrophages. However, the functional...
ORGANISM(S): Mus musculus 
2025-08-01 | GSE273731 | GEO
GenomicsHomo sapiens
Transcriptomic Characterization of LIPA+/+ and LIPA-/- iPSC-derived Macrophages
PRJNA391170 | ENA
TranscriptomicsUnderstanding the role of LIPA mediated lipophagy in pancreatic beta cells.
Pancreatic beta cells are central to insulin secretion and glucose homeostasis, and their dysfunction underlies the pathogenesis of diabetes. Lysosomal Acid Lipase (LIPA) mediates breakdown of neutral lipids within lysosomes, yet its specific function in islet biology remains poorly understood. In t...
ORGANISM(S): Rattus norvegicus 
2026-09-01 | GSE309694 | GEO
GenomicsThe effects of myeloid-specific Lipa overexpression on the transcriptomic profile of peritoneal macrophages in Ldlr-/- mice [PM_RNAseq]
The effects of myeloid-specific Lipa overexpression on the transcriptomic profile of peritoneal macrophages in Ldlr-/- mice [PM_RNAseq]
PRJNA1016388 | ENA
TranscriptomicsTargeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress
Triple-negative breast cancer (TNBC) has a poor clinical outcome, due to a lack of actionable therapeutic targets. Herein we define lysosomal acid lipase A (LIPA) as a viable molecular target in TNBC and identify a stereospecific small molecule (ERX-41) that binds LIPA. ERX-41 induces endoplasmic re...
ORGANISM(S): Homo sapiens 
2022-03-18 | GSE168800 | GEO
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