Sort   by:  
 Page size 
TranscriptomicsCardiac 12/15-lipoxygenase-induced inflammation is involved in heart failure
To identify a novel target for the treatment of heart failure, we examined gene expression in the failing heart. Among the genes analyzed, 12/15 lipoxygenase (12/15-LOX) was markedly up-regulated in heart failure. To determine whether increased expression of 12/15-LOX causes heart failure, we establ...
ORGANISM(S): Rattus norvegicus 
2009-06-06 | E-GEOD-16199 | biostudies-arrayexpress
ProteomicsHydrogen exchange soybean lipoxygenase
Defining specific pathways for efficient heat transfer from protein-solvent interfaces to their active sites represents one of the compelling and timely challenges in our quest for a physical description of the origins of enzyme catalysis. Enzymatic hydrogen tunneling reactions constitute excellent ...
ORGANISM(S): Glycine max 
2022-02-22 | PXD006234 | Pride
Hdxms Soybean lipoxygenase 
ModelsDemin2013 - PKPD behaviour - 5-Lipoxygenase inhibitors
Demin2013 - PKPD behaviour - 5-Lipoxygenase inhibitors This model is described in the article: Systems pharmacology models can be used to understand complex pharmacokinetic-pharmacodynamic behavior: an example using 5-lipoxygenase inhibitors. Demin O, Karelina T, Svetlichn...
2024-09-02 | BIOMD0000000490 | BioModels
GenomicsModulation of microRNA processing by 5-lipoxygenase
Modulation of microRNA processing by 5-lipoxygenase
PRJNA640805 | ENA
TranscriptomicsHuman lymphedema tissues exhibit an inflammatory gene expression profile
Lymphedema (LD) is characterized by the accumulation of protein-rich interstitial fluid, lipids and a significant inflammatory cell infiltrate in the limb. It causes a significant morbidity and is a common disabling disease affecting more than 150 million people worldwide, however there is no yet cu...
ORGANISM(S): Homo sapiens 
2023-06-09 | E-MTAB-13019 | biostudies-arrayexpress
GenomicsHuman 5-lipoxygenase regulates transcription by association to euchromatin [RNA-seq]
Human 5-lipoxygenase regulates transcription by association to euchromatin [RNA-seq]
PRJNA824116 | ENA
TranscriptomicsGene expression analysis of 15-Lipoxygenase 2 (15-LOX2) transgenic mice
15-Lipoxygenase 2 (15-LOX2), a human-specific lipid-peroxidizing enzyme, is mainly expressed in luminal compartment of the normal prostate and often decreased or lost in prostate cancer (PCa). Previous studies from our lab implicate 15-LOX2 as a functional tumor suppressor. To better understand the ...
ORGANISM(S): Mus musculus 
2010-12-16 | E-GEOD-15827 | biostudies-arrayexpress
GenomicsHuman 5-lipoxygenase regulates transcription by association to euchromatin [ChIP-seq]
Human 5-lipoxygenase regulates transcription by association to euchromatin [ChIP-seq]
PRJNA824076 | ENA
GenomicsHuman 5-lipoxygenase regulates transcription by association to euchromatin [FAIRE-seq]
Human 5-lipoxygenase regulates transcription by association to euchromatin [FAIRE-seq]
PRJNA824081 | ENA
TranscriptomicsNeutrophil-induced lipoxygenase subtype promotes resolution of acute lung injury in mice
Neutrophils are first responders to injury, playing a crucial role in mediating early inflammation. Recently, additional roles for neutrophils have been postulated in tissue repair and resolution of inflammation. Here, we identified a distinct subset of SiglecF+ neutrophils that emerged during mouse...
ORGANISM(S): Mus musculus 
2025-12-23 | GSE309959 | GEO
Sort   by:  
 Page size