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ModelsHayashi1999_NOSynth_Phospho
This model features the phosphorylation of rat brain neuronal NOS expressed in E. coli or Sf9 cells, which leads to a decrease in Vmax of the phosphorylated enzyme, with little change of both the Km for L-arginine and Kact for CaM. This is based on Hayashi Y. et al. J Biol Chem. (1999) 274(29):20597...
2005-01-01 | MODEL4780784080 | BioModels
TranscriptomicsCXCL4 induces a unique transcriptome in monocyte-derived macrophages
Human blood monocytes were differentiated over six days with either 100 ng/ml M-CSF or 1 umol/l CXCL4 In atherosclerotic arteries, blood monocytes differentiate to macrophages in the presence of growth factors like macrophage colony-stimulation factor (MCSF) and chemokines like platelet factor 4 (CX...
ORGANISM(S): Homo sapiens 
2010-03-07 | E-GEOD-20484 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of confluent human umbilical vein endothelial cells to stimulation with the related cytokines interleukin-1b or interleukin-33.
The similar response of endothelial cells to exogenous IL-33 or IL-1M-NM-2 prompted us to compare the genome-wide transcription profile of confluent human umbilical vein endothelial cell (HUVEC) cultures after 4 hours exposure to IL-33 or IL-1M-NM-2. Analysis of these data revealed a striking simila...
ORGANISM(S): Homo sapiens 
2013-03-05 | E-GEOD-37624 | biostudies-arrayexpress
UnknownLittle evidence of a road-effect zone for nocturnal, flying insects.
Not available
S-EPMC6342180 | biostudies-literature
UnknownPhase II study of bevacizumab in patients with HIV-associated Kaposi's sarcoma receiving antiretroviral therapy.
Not available
S-EPMC3383119 | biostudies-literature
GenomicsMigration-related phenotypic divergence is associated with epigenetic variation in rainbow trout
Migration is essential for the reproduction and survival of many animals, yet little is understood about its underlying molecular mechanisms. We used the salmonid Oncorhynchus mykiss to gain mechanistic insight into smoltification, which is a morphological, physiological, and behavioral transition u...
ORGANISM(S): Oncorhynchus mykiss 
2015-06-18 | E-GEOD-62195 | biostudies-arrayexpress
UnknownCXC chemokine ligand 4 induces a unique transcriptome in monocyte-derived macrophages.
Not available
S-EPMC3418140 | biostudies-literature
UnknownPTEN and the PTEN-like phosphatase CnrN have both distinct and overlapping roles in a Dictyostelium chemorepulsion pathway.
Not available
S-EPMC11317092 | biostudies-literature
TranscriptomicsTranscriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology
Background: Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessation of the maternal-offspring bond and is often accompanied by housing. While mu...
ORGANISM(S): Bos taurus 
2012-06-25 | E-GEOD-37447 | biostudies-arrayexpress
TranscriptomicsExpanding the Pathways of Manganese Homeostasis: Role of a Small Manganese Chaperone Protein, MntS
Escherichia coli possesses >65 small proteins of <50 amino acids, many of which are uncharacterized. We have identified a new small protein, MntS, involved in manganese homeostasis. Manganese is a critical micronutrient, serving as an enzyme cofactor and protecting against oxidative stress. Yet mang...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2011-12-08 | E-GEOD-25318 | biostudies-arrayexpress
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