To investigate the important function of membrane protein TMEM225 in sperm, we constructed Tmem225 knockout mice. Sperm from knockout mice and control mice were isolated for proteomic analysis.
Background: Metabolic dysfunction–associated steatotic liver disease (MASLD) progresses from simple steatosis to metabolic dysfunction–associated steatohepatitis (MASH), yet its therapeutic development has been hampered by pathological complexity and heterogeneity. Methods: Bulk RNA-seq and diet-in...