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TranscriptomicsGene expression microarray for mouse ES cells vs. mouse ES cells treated with 48 hr N2B27
Core circuits of transcription factors stabilize stem and progenitor cells by suppressing genes required for differentiation. We do not know how such core circuits are reorganized during cell fate transitions to allow differentiation and lineage choice to proceed. Here, we asked how the pluripotenc...
ORGANISM(S): Mus musculus 
2011-05-03 | E-GEOD-29005 | biostudies-arrayexpress
UnknownDietary determinants of serum total cholesterol among middle-aged and older adults: a population-based cross-sectional study in Dar es Salaam, Tanzania.
Not available
S-EPMC5663012 | biostudies-literature
TranscriptomicsHemangioblast skewing from embryonic stem(ES) cells by defined factors
Successful derivation of a specific cell lineage from pluripotent stem cells will tremendously facilitate the clinical usage of pluripotent stem derived somatic cells. Herein, we demonstrate that ER71/Etv2, GATA2 and Scl form a core network in hemangioblast development and that transient co-expressi...
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-45147 | biostudies-arrayexpress
TranscriptomicsZscan4 transiently reactivates early embryonic genes during the generation of induced pluripotent stem cells Part B
The generation of induced pluripotent stem cells (iPSCs) by the forced expression of defined transcription factors in somatic cells holds great promise for the future of regenerative medicine. However, due to a poor understanding of the initial reprogramming mechanism, it is difficult to control the...
ORGANISM(S): Mus musculus 
2012-01-06 | E-GEOD-31423 | biostudies-arrayexpress
TranscriptomicsAnalysis of the RDR6-dependent ein5 ski2 transcriptome profile in Arabidopsis
Post-transcriptional gene silence (PTGS) is employed in plants to shut down transgenes, invading viral genes and a certain group of endogenous genes. Meanwhile, it is not clear how the risk of expansive PTGS from endogenous genes featured by transitive siRNA production is minimized. Here we demonstr...
ORGANISM(S): Arabidopsis thaliana 
2015-04-13 | E-GEOD-52407 | biostudies-arrayexpress
UnknownAgents of change among people living with HIV and their social networks: stepped-wedge randomised controlled trial of the NAMWEZA intervention in Dar es Salaam, Tanzania.
Not available
S-EPMC6528754 | biostudies-literature
TranscriptomicsControl of Embryonic Stem Cell Lineage Commitment by Core Promoter Factor, TAF3 (RNA-Seq data)
We report that TAF3, a TBP-associated core promoter factor, is highly enriched in ES cells. In addition to its role in the core promoter recognition complex TFIID, genome-wide binding studies reveal that TAF3 localizes to chromosomal regions bound by CTCF and cohesin. Enrichment for TAF3/CTCF/cohesi...
ORGANISM(S): Mus musculus 
2011-09-02 | E-GEOD-31271 | biostudies-arrayexpress
UnknownSETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells.
Not available
S-EPMC4561491 | biostudies-literature
TranscriptomicsTranscriptomic Comparison of Neuronal Development Stages using Induced Pluripotent Stem Cells from Bipolar Disorder Patients
Fibroblasts from patients with Type I bipolar disorder (BPD) and their unaffected siblings were obtained from an Old Order Amish pedigree with a high incidence of BPD and reprogrammed to induced pluripotent stem cells (iPSCs). Established iPSCs were subsequently differentiated into neuroprogenitors ...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-74358 | biostudies-arrayexpress
GenomicsControl of Embryonic Stem Cell Lineage Commitment by Core Promoter Factor, TAF3 (ChIP-Seq data)
We report that TAF3, a TBP-associated core promoter factor, is highly enriched in ES cells. In addition to its role in the core promoter recognition complex TFIID, genome-wide binding studies reveal that TAF3 localizes to chromosomal regions bound by CTCF and cohesin. Enrichment for TAF3/CTCF/cohesi...
ORGANISM(S): Mus musculus 
2011-09-02 | E-GEOD-31270 | biostudies-arrayexpress
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