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UnknownThe role of lactic acid adsorption by ion exchange chromatography.

Background

The polyacrylic resin Amberlite IRA-67 is a promising adsorbent for lactic acid extraction from aqueous solution, but little systematic research has been devoted to the separation efficiency of lactic acid under different operating conditions.

Methodology/principal findings

S-EPMC2978715 | biostudies-literature
UnknownGlobal immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression.
Diverse immune cells in the tumor microenvironment form a complex ecosystem, but our knowledge of their heterogeneity and dynamics within hepatocellular carcinoma (HCC) still remains limited. To assess the plasticity and phenotypes of immune cells within HBV/HCV-related HCC microenvironment at singl...
S-EPMC7721904 | biostudies-literature
UnknownSingle-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma.
Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by performing single-cell RNA sequencing on 144,878 cells from 14 pairs of iCCA tumors and non-tumor liver tissues, we find that S100P and SPP1 a...
S-EPMC8960779 | biostudies-literature
UnknownStromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma.
Dissecting the spatial heterogeneity of cancer-associated fibroblasts (CAFs) is vital for understanding tumor biology and therapeutic design. By combining pathological image analysis with spatial proteomics, we revealed two stromal archetypes in hepatocellular carcinoma (HCC) with different biologic...
S-EPMC11772884 | biostudies-literature
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