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ProteomicsLoss of Drosophila nucleostemin 1 disrupts ribosomal protein homeostasis and rRNA processing to trigger apoptosis via the Xrp1/Irbp18 complex
In this study, we investigate the role of Ns1 in proliferating epithelial tissues using the Drosophila wing imaginal disc as a model. We demonstrate that knocking down Ns1 in wing discs leads to strong apoptosis. However, unlike the reported effect on overexpressed RPs, we did not observe nucleolar ...
ORGANISM(S): Drosophila Melanogaster 
2026-03-02 | PXD075076 |
ProteomicsMass spectrum data for the manuscript "Mitochondriomics reveals the underlying neuoprotective mechanism of TrkB receptor agonist R13 in the 5xFAD mice"
This is the original mass spectrometry data, which includes 45 mass spectra data and a search database table. All these data and sample processing methods can refer to the ca in the manuscript
ORGANISM(S): Mus Musculus 
2021-02-19 | PXD024268 |
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