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ProteomicsDose-Dependent Inhibition of Protein Glycosylation Reveals Crosstalk Between Glycosylation and Phosphorylation in EGF Signaling Pathways
Protein glycosylation and phosphorylation play critical roles in regulating diverse cellular processes, yet their interplay remains underexplored. This study employed a dose-dependent glycosylation inhibition to investigate the function of glycosylation, especially in phosphorylation in epidermal gr...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD071440 | Pride
Tunicamycin Glycosylation Phosphorylation Proteomic Egf 
ProteomicsCharacterizing the Effects of Protein Glycosylation Perturbation on Phosphorylation Signaling
This study investigates how engineered N-glycan remodeling affects phosphorylation signaling networks in human cells. We generated a glycoengineered HEK293 cell line (AI) with eliminated core fucosylation, enhanced sialylation, and reduced GlcNAc branching through sequential CRISPR/Cas9 knockouts (F...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD071742 | Pride
Proteomics Glycosylation Phosphorylation Serum starvation Serum stimulation Glycoengineering 
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