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GenomicsChromatin modification by SUMO-1 stimulates the promoters of translation machinery genes
We determined the occupancy of SUMO-1 on chromatin in HeLa cells by use of chromatin affinity purification coupled with next generation sequencing 18 samples examined in syncrhonized HeLa cells: Cells in G1, early S (S0)/mid (S3)/ late S phase (S6), and mitosis (M), triplicates for each sample. 1 Ch...
ORGANISM(S): Homo sapiens 
2012-10-02 | E-GEOD-41264 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of siliques at 4 developmental stages in Arabidopsis
To search for the differential expressed genes during post-fertilization and embryonic development in Arabidopsis, We profiled transcriptome of siliques at 4 developmental stages using RNA-seq based on poly(A) selection. Each RNA library yielded 100 million 101-bp paired-end reads.Using Tophat and C...
ORGANISM(S): Arabidopsis thaliana 
2016-03-28 | E-GEOD-55866 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of noncoding RNAs in maize (paired-end)
To identificate long noncoding RNAs in maize, we profiled transcriptome of shoots and roots using non-directional paired-end RNA-seq based on poly(A) selection. Transcriptom profiling in maize shoots and roots.
ORGANISM(S): Zea mays subsp. mays 
2015-11-25 | E-GEOD-56459 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of noncoding RNAs in maize (single-end)
To identificate long noncoding RNAs in maize, we profiled transcriptome of shoots and roots using stranded single-end RNA-seq based on poly(A) selection. Transcriptom profiling in maize shoots and roots.
ORGANISM(S): Zea mays subsp. mays 
2015-11-25 | E-GEOD-56460 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of various organs at different developmental stages in rice (single-end)
To identificate long noncoding RNAs in rice, we profiled transcriptome of various organs at different developmental stages using stranded single-end RNA-seq based on poly(A) selection. Transcriptom profiling in flower buds, flowers, flag leaves and roots sampled before flowering and after flowering,...
ORGANISM(S): Oryza sativa Japonica Group 
2015-11-25 | E-GEOD-56463 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of various organs at different developmental stages in rice (paired-end)
To identificate long noncoding RNAs in rice, we profiled transcriptome of various organs at different developmental stages using nondirectional paired-end RNA-seq based on poly(A) selection. Transcriptom profiling in flower buds, flowers, flag leaves and roots sampled before flowering and after flow...
ORGANISM(S): Oryza sativa Japonica Group 
2015-11-25 | E-GEOD-56462 | biostudies-arrayexpress
TranscriptomicsIdentification of CLF-regulated transcripts in embryos at the mature-green stage by strand-specific RNA-sequencing in Arabidopsis
CURLY LEAF (CLF), the major histone methyltransferase of Polycomb Repressive Complex 2 (PRC2), modifies trimethylation of histone H3 lysine 27 (H3K27me3) and mediates dynamical chromatin repression in Arabidopsis. Our previous results suggested that CLF may play regulatory roles on seed size and lip...
ORGANISM(S): Arabidopsis thaliana 
2016-03-28 | E-GEOD-68080 | biostudies-arrayexpress
ProteomicsTargeting PILRα, an immune checkpoint mediating T cell suppression, for cancer immunotherapy
One of the most successful therapies in cancer treatment involves immune checkpoint blockade using the anti-programmed death-1 (anti-PD-1)/programmed death-ligand 1 (PD-L1) antibody, which targets the interaction between tumors and T cells. However, the overall response rate is < 30% in patients wit...
ORGANISM(S): Homo Sapiens 
2024-01-25 | PXD048903 |
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