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ProteomicsLoss of Fbxo45 in AT2 cells leads to insufficient histone supply and initiates lung adenocarcinoma
We identified proteins that interact with FBXO45 and UPF1 through mass spectrometry.
ORGANISM(S): Homo Sapiens 
2024-10-29 | PXD057326 |
ProteomicsHypoxia Regulates Overall mRNA Homeostasis by Inducing Met1-linked Linear Ubiquitination of AGO2 in Cancer Cells
Hypoxia is the most prominent feature in human solid tumors and induces activation of hypoxia-inducible factors and their downstream genes to promote cancer progression. However, whether and how hypoxia regulates overall mRNA homeostasis is unclear. Here we show that hypoxia inhibits global-mRNA dec...
ORGANISM(S): Homo Sapiens 
2021-04-06 | PXD021722 |
ProteomicsIdentification of novel urine proteomic biomarkers for high stamina in high-altitude adaptation
Ascending to high-altitude of non-high-altitude natives showed rapidly declined physical ability, but some with high-altitude adaptability were still able to maintain a high level. Our goal was to find urine biomarkers that could be used to assess people for high-altitude hypoxia adaptation with hig...
ORGANISM(S): Human Parechovirus Strain T82-0169 
2023-02-02 | PXD039791 |
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