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TranscriptomicsTranscription profiling of in vivo-derived CMS4-met cells and the in vitro-derived CMS4.sel cells using CMS4 cells as a reference sample
The CMS4 sarcoma, kindly provided by A. DeLeo (University of Pittsburgh, Pittsburgh, PA), is a solid tumor of BALB/c (H-2d) origin, which grows aggressively in naive, syngeneic hosts following a s.c. transplant. Although the parental tumor cell line forms few metastatic foci in the lungs following i...
ORGANISM(S): Mus musculus 
2005-05-08 | E-MEXP-286 | biostudies-arrayexpress
TranscriptomicsIRF8-regulated genes in primary CD11 b cells
Transcriptional profiling of IRF8-regulated genes in mouse CD11b-positive primary cells. CD11b-positive cells were isolated from spleens of age-matched wt and IRF8 KO mice, the compared for their gene expression profiles. The objective is to identify genes that are regulated by IRF8 in CD11b-positiv...
ORGANISM(S): Mus musculus 
2011-10-19 | E-GEOD-31464 | biostudies-arrayexpress
TranscriptomicsIFN-γ Upregulates Survivin and Ifi202 Expression to Induce Survival and Proliferation of Tumor-Specific T Cells
Transcriptional profiling of mouse tumor-specific cytotoxic T lymphocytes (CTL) comparing activation-induced gene expression profiles induced by tumor-specific antigen (Ag) and CD3 mAb. CTLs were stimulated with either Ag or CD3 mAb for 3 and 24 h, respectively. The stimulated CTLs were compared to ...
ORGANISM(S): Mus musculus 
2010-12-03 | E-GEOD-22890 | biostudies-arrayexpress
TranscriptomicsEndogenous Elevation of Homocysteine Induces Retinal Neuron Death in the Cystathionine-b-Synthase Mutant Mice
The effects of endogenous elevation of homocysteine on retinal gene expression were screened by microarray analysis, which was performed in triplicate (i.e., three different paired RNA samples) with RNA isolated from neural retinas of cbs+/- HM at 5-weeks after a methionine diet and age-matched wild...
ORGANISM(S): Mus musculus 
2014-04-04 | E-GEOD-56458 | biostudies-arrayexpress
GenomicsUnlock the mystery of the hard-to-sequence phage genome: discovering a novel mechanism of bacterial immunity
Whole-genome sequencing is an important way to understand the genetic information, gene function, biological characteristics, and living mechanisms of organisms. There is no difficulty to have mega-level genomes sequenced at present. However, we encountered a hard-to-sequence genome of Pseudomonas a...
ORGANISM(S): Pseudomonas phage PaP1 
2013-08-22 | E-GEOD-50100 | biostudies-arrayexpress
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