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UnknownA proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Not available
S-EPMC2682542 | biostudies-literature
UnknownPharmacologic and Genetic Downregulation of Proprotein Convertase Subtilisin/Kexin Type 9 and Survival From Sepsis.
Not available
S-EPMC10635596 | biostudies-literature
GenomicsRole of PRC2 complex components in prostate cancer cell lines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39461 | biostudies-arrayexpress
TranscriptomicsExpression data of EZH2-dependent genes in prostate cancer cell lines
EZH2 is frequently over-expressed in aggressive and metastatic solid tumors, including castration resistant prostate cancer (CRPC). We sought to determine EZH2-dependent gene expression programmes in prostate cancer progression, and found an intriguing functional switch of EZH2 from a repressor to a...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39452 | biostudies-arrayexpress
GenomicsGemone-wide maps of PRC2 complex components and chromatin states in prostate cancer cell lines
We report the high-throughput profiling of PRC2 core subunits chromatin states and histone modifications in two prostate cancer cell lines, androgen-dependent cells LNCaP and androgen-independent cells LNCaP-abl (abl). By obtaining over 1 billion bases of sequence from chromatin immunoprecipitated D...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39459 | biostudies-arrayexpress
UnknownTBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma.
Not available
S-EPMC8771836 | biostudies-literature
UnknownGenome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation.
Not available
S-EPMC7768758 | biostudies-literature
UnknownAssociation Between Genetically Proxied Lipid-Lowering Drug Targets and Renal Cell Carcinoma: A Mendelian Randomization Study.
Not available
S-EPMC8545796 | biostudies-literature
UnknownPCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damage.
Not available
S-EPMC10331474 | biostudies-literature
UnknownPyrroloquinoline quinone inhibits PCSK9-NLRP3 mediated pyroptosis of Leydig cells in obese mice.
Not available
S-EPMC10630350 | biostudies-literature
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