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MetabolomicsChanges in lipid profiles of epileptic mouse model

INTRODUCTION: Approximately 1% of the world's population is impacted by epilepsy, a chronic neurological disorder characterized by seizures. One-third of epileptic patients are resistant to AEDs, or have medically refractory epilepsy (MRE). One non-invasive treatment that exists...

2022-01-06 | MTBLS1432 | MetaboLights
TranscriptomicsTranscription profiling of mouse brown preadipocytes from wild type and IRS knock-out cell lines
Brown preadipocytes were grown to confluence and synchronized by overnight serum starvation. Four independent RNA samples were analyzed from each IRS KO cell line and three independent clones of WT cells were separately analyzed as controls. Splitting of the samples resulted in a total 28 microarr...
ORGANISM(S): Mus musculus 
2007-04-06 | E-CBIL-26 | biostudies-arrayexpress
ProteomicsMouse multi-organ age-associated protein changes across life stages
Ageing is a key risk factor for disease and mortality in humans and other animals, with most insights derived from genomic, epigenomic, and transcriptomic studies. However, large-scale datasets on age-related changes at the protein level remain scarce. To fill this gap, we performed a comprehensive ...
ORGANISM(S): Mus Musculus (mouse) 
2025-06-17 | PXD058684 | JPOST Repository
ProteomicsThe senescence-associated cell surfaceome reveals potential senotherapeutic targets in human and mouse cells
Excessive accumulation of senescent cells contributes to a wide range of physiological declines and age-related pathologies. Senotherapy targeting senescent cell surface molecules represents an attractive approach to eliminate senescent cells with high specificity and accessibility. However, the com...
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2025-01-26 | PXD048921 | JPOST Repository
MetabolomicsUntargeted metabolomics workshop report: quality control considerations from sample preparation to data analysis

The Metabolomics workshop on experimental and data analysis training for untargeted metabolomics was hosted by the Proteomics Society of India in December 2019. The Workshop included six tutorial lectures and hands-on data analysis training sessions presented by seven speakers. The tutorials and ...

2020-12-17 | MTBLS1301 | MetaboLights
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