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We developed a novel approach to isolate and characterize, at nucleotide-level resolution, the RNAs derived from RNA polymerase II (Pol II) in early elongation complexes. We find that high numbers of these short RNAs are not correlated with gene expression but instead are indicative of promoter-prox...
ORGANISM(S): Drosophila melanogaster 
To advance understanding of mechanisms leading to biological and transcriptional endpoints related to estrogen action in the mouse uterus, we have mapped ERM-NM-1 and RNA polymerase II binding sites using chromatin immunoprecipitation (ChIP) followed by sequencing of enriched chromatin fragments (Ch...
ORGANISM(S): Mus musculus 
Deficiencies in the ATM gene are the underlying cause for ataxia telangiectasia, a congenital syndrome characterized by neurological, motor and immunological defects, as well as a predisposition to cancer risks. MicroRNAs (miRNAs) are small regulators of post-transcriptional gene expression and a us...
ORGANISM(S): Homo sapiens 
Deficiencies in the ATM gene are the underlying cause for ataxia telangiectasia, a congenital syndrome characterized by neurological, motor and immunological defects, as well as a predisposition to cancer risks. MicroRNAs (miRNAs) are small regulators of post-transcriptional gene expression and a us...
ORGANISM(S): Homo sapiens 
In our strudy, we preterated HepG2.2.15 cells with specific ERAP1 inhibitor ERAP1-IN-1(50μM). And then LC-MS/MS analysis was performed on a timsTOF Pro mass spectrometer.Finally we found that among the total peptides identified, ERAP1-IN-1-treated group had an reduction of the numbers of long pepti...
ORGANISM(S): Homo Sapiens 
2022-02-24 | PXD031858 |
Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-05-14 | MSV000083774 | GNPS
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