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MetabolomicsExploring the gut microbiome and serum metabolome interplay in non-functioning pituitary neuroendocrine tumors.

The gut microbiome has emerged as a potential factor in cancer pathogenesis, but its role in non-functioning pituitary neuroendocrine tumors (NF-PitNETs) remains unclear. This study aimed to elucidate gut microbiome and metabolomic alterations in NF-PitNETs by comparing microbial diversity, patho...

2025-06-16 | MTBLS12328 | MetaboLights
UnknownC. elegans enteric motor neurons fire synchronized action potentials underlying the defecation motor program.
Not available
S-EPMC9120479 | biostudies-literature
Proteomicsproteomic analyses of Mangifera indica L. in response to Xanthomonas critis pv. mangiferaeindicae
Mango bacterial leaf spot, which is caused by Xanthomonas critis pv. mangiferaeindicae (Xcm), poses a great threat to the development of mango planting industry.This work is the first to study the changes in gene and protein expressions in mango during Xcm infection. Our findings will provide new id...
ORGANISM(S): Mangifera Indica 
PXD043358 |
ProteomicsThe Pharmacological Effect and Mechanism of Lanthanum Hydroxide on Vascular Calcification Caused by Chronic Renal Failure Hyperphosphatemia
Objective: To investigate the treatment and mechanism of lanthanum hydroxide on hyperphosphate-induced vascular calcification in chronic renal failure. Methods: Develop a rat model of CKD hyperphosphatemia. Rats were randomly allocated to the model, lanthanum hydroxide, lanthanum carbonate, Calcium...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-09 | PXD023081 | Pride
Hyperphosphatemia Vascular calcification Lanthanum hydroxide Mechanism Pharmacological effect Chronic renal failure 
UnknownA novel dual Ca2+ sensor system regulates Ca2+-dependent neurotransmitter release.
Not available
S-EPMC7883739 | biostudies-literature
UnknownA novel pan-PI3K inhibitor KTC1101 synergizes with anti-PD-1 therapy by targeting tumor suppression and immune activation.
Not available
S-EPMC10938783 | biostudies-literature
ProteomicsFree rather than total iron content is critically linked to the Fur physiology in Shewanella oneidensis
Ferric uptake regulator (Fur) is a transcriptional regulator playing a central role in iron homeostasis of many bacteria and Fur inactivation commonly results in pleiotropic phenotypes. In Shewanella oneidensis, a representative of dissimilatory metal-reducing -proteobacteria capable of respiring a...
ORGANISM(S): Shewanella Oneidensis Mr-1 
2020-09-29 | PXD021732 |
ProteomicspSILAC method coupled with two complementary digestion approaches reveals PRPF39 as a new E7070-dependent DCAF15 substrate
In this study, we used a novel strategy of pSILAC method coupled with two complementary digestion approaches to find potential substrates of E7070, and reveals PRPF39 as E7070-dependent DCAF15 substrate.
ORGANISM(S): Homo Sapiens 
PXD015892 |
ProteomicsA Micro-Quantitative and FFPE-compatible Workflow for Im- 2 munohistochemistry-Guided Spatial Proteomic Analysis of 3 Cellular Subpopulations within the Tumor Microenvironment
Understanding the spatial proteomic landscape of human tumors is essential for dissecting cellular heterogeneity and microenvironmental interactions in cancer biology. Traditional bulk proteomic approaches, however, obscure spatial information and average out signals from distinct cell populations. ...
ORGANISM(S): Homo Sapiens 
PXD078338 |
ProteomicsQuantitative proteomic analysis of outer membrane vesicles from Fusobacterium nucleatum in the cancer environment
At present, the function of Fusobacterium nucleosocci outer membrane vesicles under normal intestinal environmental pH conditions has been mainly studied, but there are few studies related to the function of Fusobacterium nucleosius outer membrane vesicles under cancer microenvironment pH conditions...
ORGANISM(S): Fusobacterium Nucleatum Subsp. Vincentii 
2022-10-18 | PXD037520 |
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