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TranscriptomicsLKB1/STK11 Inactivation Leads to Expansion of Pro-Metastatic Tumor Sub-Population in Melanoma
Germline mutations in LKB1 (STK11) are associated with the Peutz–Jeghers syndrome (PJS), which includes aberrant mucocutaneous pigmentation, and somatic LKB1 mutations occur in 10% of cutaneous melanoma. By somatically inactivating Lkb1 with K-Ras activation (+/- p53 loss) in murine melanocytes, we ...
ORGANISM(S): Mus musculus 
2012-06-24 | E-GEOD-34866 | biostudies-arrayexpress
UnknownNovel PGC-1α/ATF5 Axis Partly Activates UPRmt and Mediates Cardioprotective Role of Tetrahydrocurcumin in Pathological Cardiac Hypertrophy.
Not available
S-EPMC7781724 | biostudies-literature
ProteomicsActivity Identification and Proteomics Analysis of Water-Soluble Proteins in Cocoon Coat from Different Silkworm Varieties
This study established, for the first time, a system for extracting water-soluble active proteins from the cocoon layers of multiple pigmented silkworm varieties and systematically evaluated their consistent antioxidant activities together with variety-specific antimicrobial functions. DIA-based pro...
ORGANISM(S): Bombyx Mori 
PXD076347 |
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