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ProteomicsSerum Proteomics Identifies Biomarkers for Predicting Non-survivors in Elderly COVID-19 Patients
In December 2022, China ceased the zero-COVID-19 policy, resulting in an increase in hospitalizations and deaths due to COVID-19, particularly among the elderly population. There is a pressing need to understand the disease progress and predict the survival outcomes of elderly patients to reduce the...
ORGANISM(S): Homo Sapiens 
2024-07-12 | PXD053895 |
ProteomicsA Micro-Quantitative and FFPE-compatible Workflow for Im- 2 munohistochemistry-Guided Spatial Proteomic Analysis of 3 Cellular Subpopulations within the Tumor Microenvironment
Understanding the spatial proteomic landscape of human tumors is essential for dissecting cellular heterogeneity and microenvironmental interactions in cancer biology. Traditional bulk proteomic approaches, however, obscure spatial information and average out signals from distinct cell populations. ...
ORGANISM(S): Homo Sapiens 
2026-05-14 | PXD078338 |
ProteomicsThe BPAN disease protein WDR45 forms condensates with Caprin-1 to regulate stress granule disassembly
Beta-propeller protein-associated neurodegeneration (BPAN) is a rare X-linked neurodegenerative disorder primarily caused by mutations in the WD repeat domain 45 (WDR45) gene. While WDR45 has traditionally been linked to autophagy, our study uncovers a previously unrecognized role for WDR45 as a cri...
ORGANISM(S): Homo Sapiens 
2025-04-14 | PXD062911 |
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