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MetabolomicsA metabolome atlas of mouse brain on the global metabolic signature dynamics following short-term fasting
Calorie restriction (CR) or a fasting regimen is considered one of the most potent non-pharmacological interventions to prevent chronic metabolic disorders, ameliorate autoimmune diseases, and attenuate aging. Despite efforts, the mechanisms by which CR improves health, particularly brain health, ar...
2025-07-31 | MTBLS8006 | MetaboLights
UnknownDecreased scleral Wnt5a<sup>hi</sup> fibroblasts exacerbate myopia progression by disrupting extracellular matrix homeostasis in mice.
Not available
S-EPMC12808304 | biostudies-literature
ProteomicsVIPAS39 confers ferroptosis resistance in ovarian cancer through exporting ACSL4
Ovarian cancer (OC), particularly its epithelial subtype (EOC), is the most lethal gynecological malignancy worldwide, with the majority of patients diagnosed at an advanced stage and a five-year survival rate below 30%. The standard treatment, primarily consisting of cytoreductive surgery and plati...
ORGANISM(S): Homo Sapiens 
2024-08-30 | PXD055446 |
ProteomicsAn exosome-based one-step high-throughput microfluidic platform for epithelial ovarian cancer diagnosis
Exosomes, reflecting the live cellular state, hold promise for non-invasive disease detection. However, the significance of exosome cargos has been underestimated, particularly in the clinic, mainly due to the scarcity of exosome. Here, we present a "one-step" high-throughput microfluidic platform i...
ORGANISM(S): Homo Sapiens 
2024-07-04 | PXD053690 |
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