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TranscriptomicsChIP-on-chip with anti-RBPj antibody from embryonic AGM E11.5
Hematopoietic Stem Cells (HSC) are originated during embryonic development from endothelial-like cells located in the ventral side of the dorsal aorta around day E10-12 of murine development. This region is called AGM for Aorta/Gonad/Mesonephros refering to the tissues around the hemogenic aorta. He...
ORGANISM(S): Mus musculus 
2014-10-22 | E-GEOD-52094 | biostudies-arrayexpress
TranscriptomicsGene expression from MCF7 breast cancer cells
Gene expression from MCF7 breast cancer cells at different times of TNFa incubation:pcs2 and 14-3-3 transduced cells Keywords: Expression Profiling by array We analyzed 2 arrays from each condition:MCF7-control tnf 0, MCF7-control tnf 20min, MCF-control tnf 90min, MCF7-14-3-3 tnf 0, MCF7-14-3-3 tnf...
ORGANISM(S): Homo sapiens 
2012-04-12 | E-GEOD-37139 | biostudies-arrayexpress
TranscriptomicsExpression from early pre-hematopoietic progenitors from mouse embryo
Hematopoietic Stem Cells (HSC) are originated during embryonic development from endothelial-like cells located in the ventral side of the dorsal aorta around day E10-12 of murine development. This region is called AGM for Aorta/Gonad/Mesonephros and refers to the tissues around the hemogenic aorta. ...
ORGANISM(S): Mus musculus 
2012-07-02 | E-GEOD-35395 | biostudies-arrayexpress
TranscriptomicsChromatin function of IkBa: ChIP-on-chip of IkBa
The Inhibitor of the NFkB, IkBa, is the main regulator of the NFkB pathway. Our data has demonstrated that there is an alternative function for IkBa in the chromatin that affects HOX and other developmental genes. Keywords: CHIP-chip Chip-on-chip analysis has demonstrated that IkBa associates to th...
ORGANISM(S): Mus musculus 
2013-08-28 | E-GEOD-24011 | biostudies-arrayexpress
GenomicsIkBa associates with histone H2A in human keratinocytes
Here, we demonstrate that IkBa displays a predominant and unique nuclear localization in normal basal keratinocytes. This nuclear IkBa binds the chromatin through direct interaction of the ankyrin repeats with histone H2A and associates with the promoter and regulatory regions of several development...
ORGANISM(S): Homo sapiens 
2013-08-01 | E-GEOD-30082 | biostudies-arrayexpress
TranscriptomicsThe Notch/Hes1 pathway sustains NF-M-NM-:B activation through CYLD repression in T cell leukemia
The NF-M-NM-:B pathway is a critical regulator of the immune system and has been implicated in cellular transformation and tumorigenesis. NF-M-NM-:B response is regulated by the activation state of the IM-NM-:B kinase (IKK) complex and triggered by a wide spectrum of stimuli. We previously reported ...
ORGANISM(S): Homo sapiens 
2011-05-07 | E-GEOD-20667 | biostudies-arrayexpress
UnknownDynamic chromatin association of I?B? is regulated by acetylation and cleavage of histone H4
Not available
S-SCDT-EMBOR-2021-52649V1 | biostudies-other
Unknownβ-catenin activity induces an RNA biosynthesis program promoting therapy resistance in T Acute Lymphoblastic Leukemia
Not available
S-SCDT-10_15252-EMMM_202216554 | biostudies-other
UnknownIκB kinase- coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anti-cancer therapy
Not available
S-SCDT-10_15252-EMBJ_2023114719 | biostudies-other
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