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TranscriptomicsTranscription profiling of human monocytes cultured in the presence of M-CSF for 7 days and polarized to M1 or M2 cells to characterize human monocyte-to-macrophage differentiation and polarization
Monocytes mature to macrophages in the presence of the lineage determining cytokine M-CSF. They can be further polarized into M1 or M2 macrophages with distinct functional properties. We used microarrays to detail the global programme of gene expression underlying macrophage maturation and polarizat...
ORGANISM(S): Homo sapiens 
2007-11-02 | E-GEOD-5099 | biostudies-arrayexpress
TranscriptomicsExpression data from macrophage maturation and polarization c-Myc in alternative macrophage activation experiments
In response to microenvironmental signals macrophages undergo different activation, indicated as classic/M1 and alternative/M2 polarization. C-Myc transcription factor could be an essential player in M2 polarization. Functional relevance of c-Myc in M2 macrophage biology is investigated by evaluatin...
ORGANISM(S): Homo sapiens 
2011-09-15 | E-GEOD-32164 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat thyroid cell lines after TSH-stimulation
A time-course analysis of TSH-stimulation in two rat thyroid cell lines (FRTL5 and FRT/TSHR) was performed. The expression levels of 8,784 transcripts were measured at three different time points, i.e. before (0), 30 minutes (30m) and 17 hours (17h) after TSH stimulation, by means of Affymetrix RG-U...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5115 | biostudies-arrayexpress
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