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GenomicsDeep sequencing of the murine Igh repertoire reveals complex regulation of non-random V gene rearrangement frequencies
A diverse antibody repertoire is formed through the rearrangement of V, D, and J segments at the immunoglobulin heavy chain (Igh) loci. The C57BL/6 murine Igh locus has over 100 functional VH gene segments that can recombine to a rearranged DJH. While the non-random usage of VH genes is well documen...
ORGANISM(S): Mus musculus 
2013-08-05 | E-GEOD-47766 | biostudies-arrayexpress
TranscriptomicsDeep sequencing of the murine Igh repertoire reveals complex regulation of non-random V gene rearrangement frequencies (RNA-seq)
A diverse antibody repertoire is formed through the rearrangement of V, D, and J segments at the immunoglobulin heavy chain (Igh) loci. The C57BL/6 murine Igh locus has over 100 functional VH gene segments that can recombine to a rearranged DJH. While the non-random usage of VH genes is well documen...
ORGANISM(S): Mus musculus 
2013-08-05 | E-GEOD-47885 | biostudies-arrayexpress
GenomicsA Unifying Model for Molecular Determinants of the Pre-selection VM-oM-^AM-" Repertoire
Analysis of histone modifications in double negative thymocytes from RAG-/- mice For the ChIP-seq, input and immunoprecipitated DNA was given to The Scripps DNA Array Facility, where it was prepared for massively parallel sequencing on Illumina HiSeq 2000.
ORGANISM(S): Mus musculus 
2013-08-16 | E-GEOD-48817 | biostudies-arrayexpress
GenomicsH3K4me1 ChIP-seq in murine pro-B cells
H3K4me1 binding in murine pre-B cells detected by ChIP-seq. For the ChIP-seq, input and immunoprecipitated DNA was given to the TSRI Next Generation Sequencing Core (the Scripps Research Institute, La Jolla, CA, US), where it was prepared for massively parallel sequencing on Illumina HiSeq2000.
ORGANISM(S): Mus musculus 
2016-10-25 | E-GEOD-79054 | biostudies-arrayexpress
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