Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-related clear cell renal cancer cells (ccRCC) gro...
To elucidate the interplay between signal transduction and transcriptional regulation in cellular reprogramming, distinct induction routes from epiblast stem cells to naïve pluripotency were evaluated and compared.
