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TranscriptomicsTh17, Th22 and Treg cells are enriched in the healthy human cecum
Dysregulation of CD4+ T cell populations leads to intestinal inflammation, but the regional differences of these T cell populations remained unclear in the healthy population. We first used flow cytometry to show that Th17 and Th22 cells are specifically enriched in the human cecum, while Th1 and Th...
ORGANISM(S): Homo sapiens 
2014-02-22 | E-GEOD-55258 | biostudies-arrayexpress
TranscriptomicsGene expression patterns of biopsies from a colonoscopy taken in 2009 of an ulcerative colitis patient infected with Trichuris trichiura
Helminth infection may have the potential to suppress intestinal inflammation in inflammatory bowel diseases. Ulcerative colitis is more common in developed countries than in developing countries endemic for helminth infections. There are animal models, as well as clinical trials, suggesting therape...
ORGANISM(S): Homo sapiens 
2010-11-20 | E-GEOD-25277 | biostudies-arrayexpress
TranscriptomicsGene expression patterns of biopsies from a colonoscopy taken in 2007 of an ulcerative colitis patient infected with Trichuris trichiura
Helminth infection may have the potential to suppress intestinal inflammation in inflammatory bowel diseases. Ulcerative colitis is more common in developed countries than in developing countries endemic for helminth infections. There are animal models, as well as clinical trials, suggesting therape...
ORGANISM(S): Homo sapiens 
2010-11-20 | E-GEOD-25275 | biostudies-arrayexpress
TranscriptomicsGene expression patterns of biopsies from a colonoscopy taken in 2008 of an ulcerative colitis patient infected with Trichuris trichiura
Helminth infection may have the potential to suppress intestinal inflammation in inflammatory bowel diseases. Ulcerative colitis is more common in developed countries than in developing countries endemic for helminth infections. There are animal models, as well as clinical trials, suggesting therape...
ORGANISM(S): Homo sapiens 
2010-11-20 | E-GEOD-25276 | biostudies-arrayexpress
TranscriptomicsAlternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct
Macrophages adopt an alternatively activated phenotype (AAM) when activated by IL-4. While these AAMs can be derived from local proliferation of resident tissue macrophages or recruited inflammatory monocytes, it is not known whether these different AAMs are phenotypically and functionally distinct....
ORGANISM(S): Mus musculus 
2014-02-05 | E-GEOD-54679 | biostudies-arrayexpress
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