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MetabolomicsGut microecology of long COVID persisting for 2 years

Long COVID is an emerging global public health issue. The human gut microbiota (GM) has been identified as a potentially important factor influencing the development of long COVID. This study aims to understand the prevalence, risk factors and GM of long COVID persisting for 2 years in Hainan Pro...

2025-03-26 | MTBLS11718 | MetaboLights
GenomicHepatitis C Antiviral Long-term Treatment Against Cirrhosis (HALT-C)

Reprinted from http://www.haltctrial.org/

Purpose

The Hepatitis C Antiviral Long-term Treatment against Cirrhosis (HALT-C) Trial is a randomized controlled trial designed to evaluate the safety and efficacy of long-term use of pegylated inte...

phs000430 | dbGaP
MetabolomicsSequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights
GenomicsEscherichia coli C strain:C
Escherichia coli C strain:C Genome sequencing and assembly
PRJNA380607 | ENA
GenomicsCapture Hi-C identifies the chromatin interactome of colorectal cancer risk loci
Multiple regulatory elements distant to their targets on the linear genome can influence the expression of a single gene through chromatin looping. Chromosome conformation capture implemented in Hi-C allows for genome-wide agnostic characterization of chromatin contacts. However, detection of functi...
EGAS00001001085 | EGA
MetabolomicsMaize Stem Response to Long-Term Attack by Sesamia nonagrioides
Plants defend themselves against herbivores by activating a plethora of genetic and biochemical mechanisms aimed at reducing plant damage and insect survival. The short-term plant response to insect attack is well understood, but less is known about the maintenance of this response over time. We per...
2018-05-16 | MTBLS575 | MetaboLights
MetabolomicsTranscript variants of long-chain acyl-CoA synthase 1 have distinct roles in sheep lipid metabolism
Mutton has recently been identified to be a consumer favorite, and intermuscular fat is the key factor in determining meat tenderness. Long-chain acyl-CoA synthetase 1 (ACSL1) is a vital subtype of the ACSL family that is involved in the synthesis of lipids from acyl-CoA and the oxidation of fatty a...
2023-02-06 | MTBLS5808 | MetaboLights
MetabolomicsSoil microbial adaptation to carbon deprivation: Shifts in lignocellulolytic gene profiles following long-term plant exclusion

Background:

Lignocellulose represents a primary input of organic carbon (C) into soils, yet the identity of specific microorganisms and genes which drive lignocellulose turnover in soils remain poorly understood. To address this knowledge gap, we used a 10-year grassland plant-exclusion exp...

2025-07-16 | MTBLS12728 | MetaboLights
GenomicsHepatitis C Antiviral Long-term Treatment Against Cirrhosis (HALT-C)

Reprinted from http://www.haltctrial.org/

Purpose

The Hepatitis C Antiviral Long-term Treatment against Cirrhosis (HALT-C) Trial is a randomized controlled trial designed to evaluate the safety and efficacy of long-term use of pegylated inte...

phs000430.v1.p1 | EGA
MetabolomicsUntargeted Metabolomics Analysis Reveals Aberrant Long-Chain Fatty Acids Metabolism in Relapsing-Remitting Multiple Sclerosisublication title

Background: Growing evidence indicates significant alterations in fatty acid metabolism in patients with relapsing-remitting multiple sclerosis (RRMS). However, the metabolic status of long-chain fatty acids (LCFAs), including mono-unsaturated fatty acids (MUFAs) and poly-unsaturated fatty acids ...

2026-03-23 | MTBLS13949 | MetaboLights
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