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TranscriptomicsMapping of INS promoter interactions reveals its role in long-range regulation of SYT8 transcription
Insulin (INS) synthesis and secretion from pancreatic M-NM-2 cells are tightly regulated; their deregulation causes diabetes. Here we map INS-associated loci in human pancreatic islets by 4C and 3C techniques and show that the INS gene physically interacts with the SYT8 gene, located over 300 kb ...
ORGANISM(S): Homo sapiens 
2011-02-22 | E-GEOD-25862 | biostudies-arrayexpress
GenomicsCharacterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization
Recent epigenomic studies have predicted thousands of potential enhancers in the human genome. However, there has not been systematic characterization of target promoters for these potential enhancers. Using H3K4me2 as a mark for active enhancers, we identified genome-wide enhancer-promoter interact...
ORGANISM(S): Homo sapiens 
2012-01-24 | E-GEOD-32677 | biostudies-arrayexpress
UnknownEvidence for functional G-coupled protein receptors 43 and 120 in subcutaneous and intramuscular adipose tissue of Angus crossbred steers.
Not available
S-EPMC8221046 | biostudies-literature
ProteomicsMass spectrometry analysis of Extracellular vesicles derived from naive HUVEc cells or ZIKV-infected HUVEc cells
In this project, we aimed to explore the role of extracellular vesicles (EVs) in Zika virus (ZIKV) infection. We preferred antibody capture to ltracentrifugation for exosome isolation. The EVs derived from naive HUVEc cells or ZIKV-infected HUVEc cells were harvested and analyzed by mass spectrometr...
ORGANISM(S): Homo sapiens (Human) 
2023-01-19 | PXD039152 | Pride
Mass specctrometry Extracellular vesicles Zikv infection 
TranscriptomicsIdentification of Neuronal RNA Targets of TDP-43-Containing Ribonucleoprotein Complexes
We identify the RNA targets of TAR DNA-binding protein 43 (TDP-43) from cortical neurons by RNA immunoprecipitation followed by deep sequencing (RIP-seq). We identify 4352 highly enriched RNA targets of TDP-43. We determined that the canonical TDP-43 binding site (TG)n was 55.1-fold enriched in our ...
ORGANISM(S): Rattus norvegicus 
2010-11-04 | E-GEOD-25032 | biostudies-arrayexpress
UnknownLong noncoding RNAs in hepatocellular carcinoma: Novel insights into their mechanism.
Not available
S-EPMC4670950 | biostudies-literature
TranscriptomicsTranscription profiling of wheat to identify genotypic differences in water soluble carbohydrate metabolism in stem
Water soluble carbohydrates (WSC, composed of mainly fructans, sucrose, glucose and fructose) deposited in wheat stems are important carbon sources for grain filling. Variation in stem WSC concentrations among wheat genotypes is one of the genetic factors influencing grain weight and yield under wat...
ORGANISM(S): Triticum aestivum 
2008-10-26 | E-GEOD-9767 | biostudies-arrayexpress
UnknownEpidemiological trends and mid-term to long-term outcomes of acetabular fractures in the elderly in China.
Not available
S-EPMC10799810 | biostudies-literature
UnknownEconomic evaluation of short message service intervention for HIV prevention among men who have sex with men in China: a modelling study.
Not available
S-EPMC11662610 | biostudies-literature
UnknownGenome-wide identification of the adaptor protein complexes and its expression patterns analysis in foxtail millet (Setaria italica L.).
Not available
S-EPMC11694439 | biostudies-literature
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