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TranscriptomicsPost-weaning blood transcriptomic differences between Yorkshire pigs divergently selected for residual feed intake
Global gene expression profiles of peripheral blood of 35 to 42 day-old Yorkshire pigs with extremely low (more efficient) and high RFI (less efficient) values from two Iowa State University lines (the low RFI line, n = 15, and the high RFI line, n =16) that were divergently selected for RFI during...
ORGANISM(S): Sus scrofa 
2016-01-15 | E-MTAB-4179 | biostudies-arrayexpress
TranscriptomicsRNA-seq of porcine peripheral whole blood from pig divergently selected for residual feed intake and treated with lipopolysaccharide
Yorkshire pigs were divergently selected for residual feed intake (RFI) for 8 generations. Pigs with low RFI have reduced feed intake. Based on the resource allocation theory, we hypothesize that these low RFI pigs might have compromised immune response to immune stimulation. To test this hypothesis...
ORGANISM(S): Sus scrofa 
2017-03-24 | E-MTAB-5606 | biostudies-arrayexpress
UnknownComputational and data driven molecular material design assisted by low scaling quantum mechanics calculations and machine learning.
Not available
S-EPMC8612375 | biostudies-literature
TranscriptomicsChromosomal origin utilisation in Haloferax meiditerranei wild type and mutant strains
We have comprehensively explored the origin utilisation in Haloferax mediterranei. Here we report three active chromosomal origins by genome-wide replication profiling, and demonstrate that when these three origins are deleted, a dormant origin becomes activated. Genomic DNA was extracted from the H...
ORGANISM(S): Haloferax mediterranei 
2015-07-08 | E-GEOD-70597 | biostudies-arrayexpress
TranscriptomicsLncRNA-sequence to compare the transcriptional profiles of nuclear and plastidic genes in the atnusg and the wild-type
Total RNA was isolated from two-week-old wild-type and atnusg mutant young leaves.
ORGANISM(S): Arabidopsis thaliana 
2022-05-28 | E-MTAB-11685 | biostudies-arrayexpress
ProteomicsSilver binding proteins in S. aureus
The rapid emergence of drug resistant Staphylococcus aureus (S. aureus), in particular, methicillin-resistant S. aureus (MRSA) poses a serious threat to public health globally. Reuse of metal-based antimicrobials stands for one of the most promising strategies to resensitize drug resistant bacteria ...
ORGANISM(S): Staphylococcus aureus 
2021-09-10 | PXD025106 | Pride
Silver-binding protein S. aureus 
TranscriptomicsThe IRE1α-XBP1 Pathway of the Unfolded Protein Response is Required for Adipogenesis
Signaling cascades during adipogenesis culminate in the expression of two essential adipogenic factors, PPARγ and C/EBPα. Here we demonstrate that the IRE1α-XBP1 pathway, the most conserved branch of the unfolded protein response (UPR), is indispensable for adipogenesis. Indeed, XBP1-deficient ...
ORGANISM(S): Mus musculus 
2010-06-19 | E-GEOD-15771 | biostudies-arrayexpress
TranscriptomicsThe ER-Associated Degradation Adapter Protein Sel1L Regulates Triglyceride Metabolism via Lipoprotein Lipase
Sel1L is an adaptor protein for the E3 ligase Hrd1 in the endoplasmic reticulum-associated degradation (ERAD), but its physiological role in a cell-type-specific manner remains unclear. Here we show that mice with adipocyte-specific Sel1L deficiency are resistant to diet-induced obesity and exhibit ...
ORGANISM(S): Mus musculus 
2015-05-18 | E-GEOD-56918 | biostudies-arrayexpress
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