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TranscriptomicsLong-term adaptation to hypoxic conditions - Febit transcriptome analysis
Aspergillus fumigatus is an opportunistic, airborne pathogen causing invasive aspergillosis in immunocompromised patients. During the infection process A. fumigatus is challenged by hypoxic microenvironments occurring in inflammatory, necrotic tissue. To gain further insights into the adaptation mec...
ORGANISM(S): Aspergillus fumigatus 
2014-07-01 | E-MTAB-2699 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of neuroendocrine-like LNCaP-cells
The main purpose of the experiment is to look for changes in the transcriptome of LNCaP cells during neuroendocrine differentiation induced by incubation in steroid stripped serum (charcoal treated fetal bovine serum) for four days.
ORGANISM(S): Homo sapiens 
2006-10-31 | E-TABM-78 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Several studies indicate that omega (n)-3 fatty acids may have a potential in the prevention and treatment of cancer. In this study the colon cancer cell lines SW480 and SW620 were treated with the n-3 PUFA DHA (Docosahexaenoic acid) for 3 different time points (12, 24 and 48h). The experiments were...
ORGANISM(S): Homo sapiens 
2008-04-01 | E-MEXP-1014 | biostudies-arrayexpress
ProteomicsQuantitative Proteomics Analysis of the Cervicovaginal Mucus from 4 Individual Donors
The goal of this study was to identify amylases that might be present in the vaginal fluid from four individual donors coming either from the microbiome or expressed by the human donors in these fluids. We collected cervicovaginal mucus from 4 donors, characterized the species composition of vaginal...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-05 | MSV000085378 | MassIVE
TranscriptomicsRapid evolution of phenotypic plasticity and shifting thresholds of genetic assimilation in the nematode Caenorhabditis remanei
Many organisms can acclimate to new environments through phenotypic plasticity, a complex trait that can be heritable, subject to selection, and evolve. However, the rate and genetic basis of plasticity evolution remain largely unknown. We experimentally evolved outbred populations of the nematode C...
ORGANISM(S): Caenorhabditis remanei 
2014-05-04 | E-GEOD-56510 | biostudies-arrayexpress
TranscriptomicsExpression and differential expression analysis of HFF cells in G0 phase compared to cells in G1 using nONCOchip 2.0 array
Expression and differential expression analysis of long non-coding RNAs and protein-coding genes. HFF cells were synchronised by serum starvation and reside in G0 phase or G1 phase of mitotic cell cycle. We analyzed three arrays each for HFF cells in G0 phase and cells in G1 phase
ORGANISM(S): Homo sapiens 
2015-01-23 | E-GEOD-61006 | biostudies-arrayexpress
TranscriptomicsTGF-β1 Accelerates Dendritic Cell Differentiation from Common Dendritic Cell Progenitors (CDPs) and Directs Subset Specification Towards Conventional Dendritic Cells
Dendritic cells (DCs) in lymphoid tissue comprise conventional DCs (cDCs) and plasmacytoid DCs (pDCs) that develop from common DC progenitors (CDPs). CDPs are Flt3+c-kitintM-CSFR+ and reside in bone marrow. Here we describe a two-step culture system that recapitulates DC development from c-kithiFlt3...
ORGANISM(S): Mus musculus 
2010-10-04 | E-GEOD-22432 | biostudies-arrayexpress
TranscriptomicsAn Integrated Analysis of Molecular Acclimation to High Light in the Marine Diatom Phaeodactylum tricornutum
Photosynthetic diatoms are exposed to rapid and unpredictable changes in irradiance and spectral quality, and must be able to adapt their light harvesting systems to varying light conditions. Molecular mechanisms behind light acclimation in diatoms are largely unknown. We set out to investigate the ...
ORGANISM(S): Phaeodactylum tricornutum 
2009-11-05 | E-GEOD-17237 | biostudies-arrayexpress
TranscriptomicsSystem responses to equal doses of photosynthetically usable radiation of blue, green, and red light in the marine diatom Phaeodactylum tricornutum.
We have studied the transcriptional, metabolic and photo-physiological responses to light of different spectral quality in the marine diatom Phaeodactylum tricornutum through time-series studies of cultures exposed to equal doses of photosynthetically usable radiation of blue, green and red light. T...
ORGANISM(S): Phaeodactylum tricornutum 
2014-12-22 | E-GEOD-55959 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of BDC2.5 CD4T cells isolated from NOD mice after in vivo antigen stimulation with either DEC205+ or DCIR2+ DCs.
We identified DCIR2+DCs but not DEC205+DCs as able to induce peripheral T cell tolerance in pre-diabetic autoimmune NOD mice. To determine what distinct genetic programs are elicited in the auto-reactive CD4 T cells early after stimulation by these two DC subsets, we utilized adoptive transfer of BD...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-69554 | biostudies-arrayexpress
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