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MetabolomicsExamination of human osteoarchaeological remains as a feasible source of polar and apolar metabolites to study past conditions
Metabolomics is a modern tool that aids in our understanding of the molecular changes in organisms. Archaeological science is a branch of archaeology that explores different archaeological materials using modern analytical tools. Human osteoarchaeological material are a frequent finding in archaeolo...
2022-07-04 | MTBLS4437 | MetaboLights
MetabolomicsHuman Archaeological Dentin as Source of Polar and Less Polar Metabolites for Untargeted Metabolomic Research: The Case of Yersinia pestis
Metabolomic approaches, such as in clinical applications of living individuals, have shown potential use for solving questions regarding the past when applied to archaeological material. Here, we study for the first time the potential of this Omic approach as applied to metabolites extracted from ar...
2024-03-15 | MTBLS7394 | MetaboLights
TranscriptomicsReal time quantitative PCR analysis of murine macrophages
Murine macrophages were isolated from the lungs of mice given a pulmonary challenge with C. neoformans strain H99. Mice were either given a protective (H99γ) or a mock (HKCn) immunization prior to C. neoformans H99 challenge, and macrophages were isolated from the lungs of mice 24 hours, 3 days, or ...
ORGANISM(S): Mus musculus 
2012-08-09 | E-GEOD-39990 | biostudies-arrayexpress
TranscriptomicsIdentification of high temperature and daylength responsive genes in barley
High temperature influences plant development and can reduce crop yields. We used the Agilent Barley Gene Expression Microarray to identify high temperature responsive genes in cereals. In temperate cereals, such as wheat and barley, high temperature results in rapid progression through reproductive...
ORGANISM(S): Hordeum vulgare 
2012-04-03 | E-GEOD-33938 | biostudies-arrayexpress
TranscriptomicsRole of SPI-1 Secreted Effectors, SipA, SopABDE2, in Acute Bovine Response to Salmonella enterica Serovar Typhimurium
Salmonella enterica Serovar Typhimurium (S. Typhimurium) causes enterocolitis in humans and calves characterized by diarrhea and polymorphonuclear cell (PMN) influx to the intestinal mucosa. The Salmonella Type III Secretion System encoded at Pathogenicity Island I (SPI-1) translocates the Salmonel...
ORGANISM(S): Bos taurus 
2012-01-10 | E-GEOD-13847 | biostudies-arrayexpress
UnknownLong-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial.
Not available
S-EPMC4858585 | biostudies-literature
TranscriptomicsParental binge alcohol abuse alters F1 generation hypothalamic gene expression in the absence of direct fetal alcohol exposure
Adolescent binge alcohol exposure has been previously shown to have long-lasting effects on the expression of hypothalamic genes that regulate the stress response, even in the absence of subsequent adult alcohol exposure. Those data suggested that alcohol can induce permanent gene expression changes...
ORGANISM(S): Rattus norvegicus 
2014-03-19 | E-GEOD-53028 | biostudies-arrayexpress
UnknownCentral Nervous System Idiopathic Inflammatory Demyelinating Disorders in South Americans: A Descriptive, Multicenter, Cross-Sectional Study.
Not available
S-EPMC4519274 | biostudies-literature
TranscriptomicsA potential role for snoRNA in PKR activation during metabolic stress
PKR (Protein Kinase RNA-activated) is activated by metabolic stress, such as that associated with obesity, and this activation depends on its RNA-binding domain. Here we investigated whether endogenous RNA triggers PKR activation in response to lipid exposure. Our results indicate that snoRNAs (smal...
ORGANISM(S): Mus musculus 
2015-05-08 | E-GEOD-66540 | biostudies-arrayexpress
UnknownMeasuring The Lifetime Costs Of Serious Mental Illness And The Mitigating Effects Of Educational Attainment.
Not available
S-EPMC6597007 | biostudies-literature
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