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TranscriptomicsA Y-chromosome-encoded small RNA acts as sex determinant in persimmons
In plants, multiple lineages have evolved sex chromosomes independently, providing a powerful comparative framework, but few specific determinants controlling the expression of a specific sex have been identified. We investigated sex-determinants in Caucasian persimmon, Diospyros lotus, a dioecious ...
ORGANISM(S): Diospyros lotus 
2014-11-04 | E-GEOD-61386 | biostudies-arrayexpress
GenomicsFlexible chromatin loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire
The immunoglobulin heavy-chain (Igh) locus undergoes large-scale contraction in pro-B cells, which facilitates VH-DJH recombination by juxtaposing distal VH genes next to the DJH- rearranged gene segment in the proximal Igh domain. By high-resolution mapping of long-range interactions, we now demons...
ORGANISM(S): Mus musculus 
2013-09-30 | E-GEOD-43008 | biostudies-arrayexpress
TranscriptomicsM. sedula transcriptional response to ferrous iron and RISC supplements
Abstract: The crenarchaeal order Sulfolobales collectively contains at least five major terminal oxidase complexes. Based on genome sequence information, all five complexes are found only in Metallosphaera sedula and Sulfolobus tokodaii, the two sequenced Sulfolobales capable of iron oxidization. Wh...
ORGANISM(S): Metallosphaera sedula 
2008-10-22 | E-GEOD-12044 | biostudies-arrayexpress
UnknownDynamic evolution of great ape Y chromosomes.
Not available
S-EPMC7585023 | biostudies-literature
TranscriptomicsNative elongating transcript sequencing (NET-seq) of wild type Saccharomyces cerevisiae and of DST1, RCO1, SET1, SET2, EAF3 deletion strains
We present an approach (native elongating transcript sequencing, NET-seq), based on deep sequencing of 3M-bM-^@M-^Y ends of nascent transcripts associated with RNA polymerase, to monitor transcription at nucleotide resolution. Application of NET-seq in Saccharomyces cerevisiae reveals that while pro...
ORGANISM(S): Saccharomyces cerevisiae 
2011-01-19 | E-GEOD-25107 | biostudies-arrayexpress
TranscriptomicsLong non-coding RNAs and microRNAs involved in integrated co-regulation of neuronal maturation [mRNA and lncRNA expression]
Neurogenesis is a pro-survival process that comprises of dendritic and axonal growth, synaptogenesis, synaptic and neuronal pruning. These complex processes are determined by temporal gene expression during development, which is in turn tightly regulated by long non-coding RNAs and microRNAs. In thi...
ORGANISM(S): Mus musculus 
2014-10-24 | E-GEOD-44833 | biostudies-arrayexpress
UnknownBiocontrol efficacy of Bacillus velezensis strain YS-AT-DS1 against the root-knot nematode Meloidogyne incognita in tomato plants.
Not available
S-EPMC9722970 | biostudies-literature
TranscriptomicsDisrupted processing of long pre-mRNAs and widespread RNA missplicing are components of neuronal vulnerability from loss of nuclear TDP-43 (CLIP)
Cross-linking and immunoprecipitation coupled with high-throughput sequencing was used to identify binding sites within 6,304 genes as the brain RNA targets for TDP-43, an RNA binding protein which when mutated causes Amyotrophic Lateral Sclerosis (ALS). Use of massively parallel sequencing and spli...
ORGANISM(S): Mus musculus 
2011-03-03 | E-GEOD-27201 | biostudies-arrayexpress
TranscriptomicsSpatial Transcriptomics of the Epipharynx in Long COVID: Exploring SARS-CoV-2 Signalling Pathways and the Therapeutic Potential of Epipharyngeal Abrasive Therapy
10X VisiumHD spatial transcriptomics of epipharynx from three patients with long COVID and two control individuals without COVID-19.
ORGANISM(S): Homo sapiens 
2025-02-24 | E-MTAB-14669 | biostudies-arrayexpress
TranscriptomicsNanoString analysis of a rat liver mRNA panel following TCDD treatment
Profiling of mRNA abundances with high-throughput platforms such as microarrays and RNA-Seq has become an important tool in both basic and biomedical research. However these platforms remain prone to systematic errors, and have challenges in clinical and industrial application. As a result it is sta...
ORGANISM(S): Rattus norvegicus 
2013-12-31 | E-GEOD-43251 | biostudies-arrayexpress
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