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TranscriptomicsIdentification and Targeted Inhibition of a Fibroblast Lineage Responsible for Scarring and Cancer Stroma
Dermal fibroblasts represent a heterogeneous population of cells with diverse features that remain largely undefined due to a lack of functional subclasses. Here we reveal the presence of multiple lineages of dermal fibroblasts within the dorsal back. Genetic lineage tracing and transplantation assa...
ORGANISM(S): Mus musculus 
2015-05-15 | E-GEOD-65402 | biostudies-arrayexpress
TranscriptomicsNeonatal Skeletal Progenitors
Prospectively isolated and characerized skeletal progenitor lineages 3 repeats per FACS sorted population
ORGANISM(S): Mus musculus 
2015-01-29 | E-GEOD-64447 | biostudies-arrayexpress
TranscriptomicsHuman bone and marrow niche formation by mesenchymal progenitors in vivo is predefined by an organotypic epigenetic signature
In this study, we have analyzed DNA methylation characteristics of human mesenchymal stem and progenitor cells (MSPCs) form different tissue sources including bone marrow (BM), white adipose tissue (WAT ), umbilical cord (UC) as well as dermal fibroblasts by using the HumanMethylation450K array. Cel...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-41933 | biostudies-arrayexpress
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