Sort   by:  
 Page size 
GenomicsFiltering and Annotation of Variants That Are Rare (FAVR)

The project developed a suite of new methods (FAVR) designed to assist the shortlisting of genetic variants under a rare variant-phenotype/disease model. The methods were designed to work with commonly used massively parallel sequencing analysis pipelines, such as the GATK or ANNOVAR, and have be...

phs000601.v1.p1 | EGA
GenomicsTracking the origins and drivers of subclonal metastatic expansion in prostate cancer
Tumour heterogeneity in primary prostate cancer is a well-established phenomenon. However, how the subclonal diversity of tumours changes during metastasis and progression to lethality is poorly understood. Here we reveal the precise direction of metastatic spread across four lethal prostate cancer ...
EGAS00001000942 | EGA
Genomicsena-DATASET-UOM-CAP-21-04-2015-13:03:14:947-502 - samples
Data from the study of subclonal metastatic expansion in prostate cancer. Whole genome shotgun sequencing of fifteen samples, tumour and whole blood, from the four initial patients.
EGAD00001001343 | EGA
Genomicsena-DATASET-UOM-CAP-21-04-2015-13:06:47:615-508 - samples
Data from the study of subclonal metastatic expansion in prostate cancer. RNA-seq of twelve samples, tumour and benign tissue, from the four initial patients.
EGAD00001001345 | EGA
Genomicsena-DATASET-UOM-CAP-21-04-2015-13:04:36:707-504 - samples
Data from the study of subclonal metastatic expansion in prostate cancer. Whole genome shotgun sequencing of six samples, tumour and whole blood, from the three additional patients whose somatic variants were examined in depth.
EGAD00001001344 | EGA
GenomicsDAC for integrated genomics of metastatic prostate cancer
Data Access Committee EGAC00001000230
EGAC00001000230 | EGA
TranscriptomicsWhole genome characterisation of chemoresistant ovarian cancer [NanoString miRNA]
Patients with high-grade serous ovarian cancer (HGSC) have experienced little improvement in overall survival, and standard treatment has not advanced beyond platinum-based combination chemotherapy, during the past 30 years. To understand the drivers of clinical phenotypes better, here we use whole-...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-65819 | biostudies-arrayexpress
TranscriptomicsWhole genome characterisation of chemoresistant ovarian cancer [Illumina_450K_Methylation]
Patients with high-grade serous ovarian cancer (HGSC) have experienced little improvement in overall survival, and standard treatment has not advanced beyond platinum-based combination chemotherapy, during the past 30 years. To understand the drivers of clinical phenotypes better, here we use whole-...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-65820 | biostudies-arrayexpress
Sort   by:  
 Page size