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GenomicsThe Scc2NIPBL/Scc4MAU2 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions [ChIP-seq]
The Scc2/Scc4 complex binds to broad nucleosome-free regions in the promoters of highly expressed genes. The cohesin loader is recruited to these sites by the RSC chromatin remodeling complex ChIp- Sequencing analysis of the distribution of Scc2 and Scc4 on budding yeast chromosomes.An input sample ...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-56993 | biostudies-arrayexpress
GenomicsThe Scc2NIPBL/Scc4MAU2 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions [Mnase-seq]
The Scc2/Scc4 complex binds to broad nucleosome-free regions in the promoters of highly expressed genes. The cohesin loader is recruited to these sites by the RSC chromatin remodeling complex MNase digestion of purified DNA followed by paired-end sequencing was performed in order to investigate geno...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-56992 | biostudies-arrayexpress
GenomicsThe Scc2NIPBL/Scc4MAU2 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-56994 | biostudies-arrayexpress
TranscriptomicsBudding yeast Wapl controls sister chromatid cohesion maintenance and the chromosome condensation status [BrdU-ChIP].
Cohesin acetylation by Eco1 during DNA replication establishes sister chromatid cohesion. We show that acetylation makes cohesin resistant to Wapl activity from S-phase until mitosis. Wapl turns out to be a key regulator of cohesin dynamics on chromosomes by controling cohesin maintenance following ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-22 | E-GEOD-42456 | biostudies-arrayexpress
TranscriptomicsBudding yeast Wapl controls sister chromatid cohesion maintenance and the chromosome condensation status [PK-ChIP]
Cohesin acetylation by Eco1 during DNA replication establishes sister chromatid cohesion. We show that acetylation makes cohesin resistant to Wapl activity from S-phase until mitosis. Wapl turns out to be a key regulator of cohesin dynamics on chromosomes by controling cohesin maintenance following ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-22 | E-GEOD-42457 | biostudies-arrayexpress
TranscriptomicsBudding yeast Wapl controls sister chromatid cohesion maintenance and the chromosome condensation status [expression]
Cohesin acetylation by Eco1 during DNA replication establishes sister chromatid cohesion. We show that acetylation makes cohesin resistant to Wapl activity from S-phase until mitosis. Wapl turns out to be a key regulator of cohesin dynamics on chromosomes by controling cohesin maintenance following ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-22 | E-GEOD-42458 | biostudies-arrayexpress
TranscriptomicsBudding yeast Wapl controls sister chromatid cohesion maintenance and the chromosome condensation status
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-22 | E-GEOD-42460 | biostudies-arrayexpress
TranscriptomicsThe Scc2NIPBL/Scc4MAU2 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions [microarray]
The Scc2/Scc4 complex binds to broad nucleosome-free regions in the promoters of highly expressed genes. The cohesin loader is recruited to these sites by the RSC chromatin remodeling complex Total RNA was isolated from wt, scc2-4 and sth1-3 cells at 25°C and 37°C. dscDNA was obtained using the IV...
ORGANISM(S): Saccharomyces cerevisiae 
2014-08-01 | E-GEOD-56991 | biostudies-arrayexpress
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