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Transcriptional analysis of one primary paraganglioma One sample (primary paraganglioma) were hybridized onto a cDNA microarray in order to investigate differentially expressed genes
ORGANISM(S): Homo sapiens 
Several mechanisms have been proposed to account for Sdh-mutation-induced tumorigenesis, the most accepted of which is based on the constitutive expression of the hypoxia-inducible factor 1alpha (Hif1alpha) at normal oxygen tension, a theory referred to as pseudo-hypoxic drive. Other molecular proce...
ORGANISM(S): Mus musculus 
Several mechanisms have been proposed to account for Sdh-mutation-induced tumorigenesis, the most accepted of which is based on the constitutive expression of the hypoxia-inducible factor 1alpha (Hif1alpha) at normal oxygen tension, a theory referred to as pseudo-hypoxic drive. Other molecular proce...
ORGANISM(S): Mus musculus 
Development and pre-clinical testing of new cancer therapies is limited by the scarcity of in vivo models that authentically reproduce tumor growth and metastatic progression. We report new models for breast tumor growth and metastasis, in the form of transplantable tumors derived directly from indi...
ORGANISM(S): Homo sapiens 
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