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A non-functional myosin Vb motor in duodenal enterocytes results in disruption of epithelial cell polarity characterized by complete loss of microvilli and mislocalization of apical brush border proteins in the cytoplasm which finally cause a devastating disease in neonates with severe malabsorption...
ORGANISM(S): Homo sapiens 

Microalgae are important primary producers and form the basis for the marine food web. As global climate changes, so do salinity levels that algae are exposed to. A metabolic response of algal cells partly alleviates the resulting osmotic stress. Some metabolites involved in the response are well...

2023-09-04 | MTBLS3177 | MetaboLights
LYSIN MOTIF DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYL INOSITOL-ANCHORED PROTEIN 2 (LYM2) is a GPI-anchored LysM receptor-like protein (LysM-RLP) that harbors three extracellular LysM-domains and a GPI moiety at the C-terminus. LYM2 in Arabidopsis thaliana is involved in chitin-mediated plasmodesmal flu...
ORGANISM(S): Populus canescens (Grey poplar) (Populus tremula x Populus alba) 
2026-09-07 | PXD058986 | Pride
Haematopoietic stem cells (HSC) reside in locations within the bone marrow microenvironment (BMM) featuring a slightly higher extracellular calcium ion concentration [eCa2+]. HSC respond to [eCa2+] via the G-protein coupled calcium-sensing receptor (CaSR), but the role of CaSR for leukaemia and leuk...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD035937 | Pride
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