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TranscriptomicsExpression data from Down syndrome and non-Down syndrome pediatric acute lymphoblastic leukemia cases
Gene expression profiling (GEP) can reveal characteristic signatures associated with distinct biologic subtypes of acute lymphoblastic leukemia (ALL). We performed GEP on Down syndrome (DS) and comparison non-Down syndrome (NDS) ALL cases to identify biologic differences between these groups. Ficoll...
ORGANISM(S): Homo sapiens 
2011-07-12 | E-GEOD-20910 | biostudies-arrayexpress
TranscriptomicsSNP data from Down syndrome and non-Down syndrome pediatric acute lymphoblastic leukemia cases and controls
SNP profiling can reveal copy number abnormalities and loss of heterozygosity associated with distinct biologic subtypes of acute lymphoblastic leukemia (ALL). We performed SNP profiling of Down syndrome ALL cases and controls to identify unique biologic features of this ALL subgroup. Ficoll-enriche...
ORGANISM(S): Homo sapiens 
2011-07-12 | E-GEOD-21091 | biostudies-arrayexpress
TranscriptomicsRearrangement of CRLF2 in B-progenitor and Down syndrome associated acute lymphoblastic leukemia
Chromosomal aneuploidy and translocations are hallmarks of acute lymphoblastic leukemia (ALL), but many patients lack a recurring chromosomal alteration. Here we report a recurring interstitial deletion of the pseudoautosomal region 1 of chromosomes X and Y in B-progenitor ALL that results in the ex...
ORGANISM(S): Homo sapiens 
2009-10-18 | E-GEOD-16724 | biostudies-arrayexpress
UnknownGenomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles.
Not available
S-EPMC4107887 | biostudies-literature
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