Sort   by:  
 Page size 
ProteomicsRecombinant SWATH library for identification of low abundant human plasma proteins
Recombinant SWATH library for identification of low abundant human plasma proteins
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-11-04 | MSV000086411 | MassIVE
TranscriptomicsMechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch
Hypoxia-induced cell injury has been related to multiple pathological conditions. In order to render hypoxia-sensitive cells and tissues resistant to low O2 environment, in this current study, we used Drosophila melanogaster as a model to dissect the mechanisms underlying hypoxia-tolerance. A D. mel...
ORGANISM(S): Drosophila melanogaster 
2010-06-25 | E-GEOD-8803 | biostudies-arrayexpress
Transcriptomics3-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product (nasal epithelial cells-microRNA dataset).
In vitro toxicology approaches have evolved, from a focus on the molecular changes within a cell to understanding of toxicity-related mechanisms that simulate the in vivo environment. The recent development of three dimensional (3-D) organotypic nasal epithelial culture models offer a physiologicall...
ORGANISM(S): Homo sapiens 
2018-04-01 | E-MTAB-6613 | biostudies-arrayexpress
GenomicsAnalysis of the Epigenomic and Transcriptional Landscapes during mammalian spermatogenesis [Bisulfite-Seq]
Adult germline stem cells (AGSCs) are multifunctional - they must self renew, maintain genome pluripotency, and prepare for gametogenesis – which involves meiotic and chromatin repackaging phases. To better understand AGSCs and gametogenesis, we derived high-resolution profiles of transcription, DNA...
ORGANISM(S): Mus musculus 
2014-05-19 | E-GEOD-49623 | biostudies-arrayexpress
TranscriptomicsRegulation of the core pre-mRNA splicing machinery by MYC and PRMT5 is essential to sustain lymphomagenesis [B-cells]
Over-expressed MYC binds to virtually all active promoters within a cell, although with different binding affinities, and modulates gene expression, both positively and negatively. Here, we show that during lymphomagenesis in Eµ-myc transgenic mice, MYC directly up-regulates the transcription of the...
ORGANISM(S): Mus musculus 
2015-05-19 | E-GEOD-60188 | biostudies-arrayexpress
GenomicsAnalysis of the Epigenomic and Transcriptional Landscapes during mammalian spermatogenesis [sperm; Bisulfite-Seq]
Adult germline stem cells (AGSCs) are multifunctional - they must self renew, maintain genome pluripotency, and prepare for gametogenesis – which involves meiotic and chromatin repackaging phases. To better understand AGSCs and gametogenesis, we derived high-resolution profiles of transcription, DNA...
ORGANISM(S): Homo sapiens 
2014-05-19 | E-GEOD-57097 | biostudies-arrayexpress
TranscriptomicsAnalysis of the Epigenomic and Transcriptional Landscapes during mammalian spermatogenesis [sperm; RNA-seq]
Adult germline stem cells (AGSCs) are multifunctional - they must self renew, maintain genome pluripotency, and prepare for gametogenesis – which involves meiotic and chromatin repackaging phases. To better understand AGSCs and gametogenesis, we derived high-resolution profiles of transcription, DNA...
ORGANISM(S): Homo sapiens 
2014-05-19 | E-GEOD-57096 | biostudies-arrayexpress
TranscriptomicsRegulation of the core pre-mRNA splicing machinery by MYC and PRMT5 is essential to sustain lymphomagenesis [fetal liver]
Over-expressed MYC binds to virtually all active promoters within a cell, although with different binding affinities, and modulates gene expression, both positively and negatively. Here, we show that during lymphomagenesis in Eµ-myc transgenic mice, MYC directly up-regulates the transcription of the...
ORGANISM(S): Mus musculus 
2015-05-19 | E-GEOD-61637 | biostudies-arrayexpress
GenomicsTranscription and Imprinting Dynamics in Developing Postnatal Male Germline Stem Cells
Paternal imprinting initiates in primordial germ cells (PGCs), and is considered largely completed at birth. The resulting postnatal spermatogonial stem cells (SSCs) thenself-renew and proliferate to populate the testicular niche, with sexual maturation enabling productive gametogenesis. mRNA profi...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-62355 | biostudies-arrayexpress
UnknownCharacteristics and outcomes of socioeconomically disadvantaged pregnant individuals with adult congenital heart disease presenting to a Cardio-Obstetrics Program.
Not available
S-EPMC11157696 | biostudies-literature
Sort   by:  
 Page size