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TranscriptomicsHIF-1synergizes with glucocorticoids to promote BFU-E progenitor self-renewal
With the aim of finding small molecules that stimulate erythropoiesis earlier than erythropoietin and that enhance CFU-E production, we studied the mechanism by which glucocorticoids increase CFU-E formation. Using BFU-E and CFU-E progenitors purified by a new technique, we demonstrate that glucocor...
ORGANISM(S): Mus musculus 
2010-12-21 | E-GEOD-26086 | biostudies-arrayexpress
TranscriptomicsIsolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E
Burst-forming unit-erythroid (BFU-E) and colony-forming unit-erythroid (CFU-E) cells are erythroid progenitors traditionally defined by colony assays. We developed a flow cytometry-based strategy for isolating human BFU-E and CFU-E cells based on the changes in expression of cell surface markers dur...
ORGANISM(S): Homo sapiens 
2014-10-30 | E-GEOD-61566 | biostudies-arrayexpress
MetabolomicsMetabolomics-Based Analysis of Adaptive Mechanism of Eleutheronema tetradactylum to Low-Temperature Stress

Temperature is a critical environmental factor influencing fish physiology. Eleutheronema tetradactylum is an economically important warm-water species, but its response to long-term cold stress remains unclear. In this study, we exposed juvenile fish to 18 °C for 7 and 14 days and investigated h...

2026-09-08 | MTBLS15459 | MetaboLights
TranscriptomicsTranscriptomic profiling of Arabidopsis exposed to E-2-hexenal
Plants are known to be responsive to volatiles, but knowledge about the molecular players involved in transducing their perception remain scarce. Here the response of Arabidopsis thaliana to E-2-hexenal, one of the green leaf volatiles that are produced upon wounding, herbivory or infection with pat...
ORGANISM(S): Arabidopsis thaliana 
2015-09-08 | E-GEOD-53957 | biostudies-arrayexpress
MetabolomicsA novel luciferin 4-monooxygenase from Galleria mellonella larval gut drives rapid low-density polyethylene biodegradation
Plastic pollution is a pressing global issue, with polyethylene (PE) the most widespread and persistent contaminant. Galleria mellonella (G. mellonella) has been identified as one of the most suitable insect species for the efficient consumption and degradation of PE; However, the gut microbiota and...
2026-04-11 | MTBLS14246 | MetaboLights
MetabolomicsMetabolo-transcriptomics analyses reveal alfalfa adaptation to combined saline-alkali and low-temperature stress in the field

Metabolomics analysis revealed specific accumulation of amino acids, organic acids, carbohydrates, fatty acids and flavonoids in ZD compared with that in BM. The core differential metabolites associated with ZD stress resistance included isoleucine, fumaric acid, raffinose and isovitexin. In...

2025-06-19 | MTBLS12611 | MetaboLights
TranscriptomicsTranscription profiling of brain, liver and spleen from rats infected with Escherichia coli K1 and treated with capsule-selective endosialidase E
Transcription profiling of infected and treated (Capsule-Selective Endosialidase E Minimizes) of RNA isolated from brain/spleen/liver of rats with E.coli K1
ORGANISM(S): Rattus norvegicus 
2010-01-10 | E-MEXP-2406 | biostudies-arrayexpress
MetabolomicsDynamic utilization of low-molecular-weight organic substrates across a microbial growth rate gradient

AIM: Low-molecular-weight organic substances (LMWOSs) are at the nexus between micro-organisms, plant roots, detritus and the soil mineral matrix. The nominal oxidation state of carbon (NOSC) has been suggested as a potential parameter for modelling microbial uptake rates of LMWO...

2023-08-14 | MTBLS3558 | MetaboLights
ProteomicsIdentification of peptides from E-Jiao
E-Jiao is a traditional Chinese medicine. In this project, we used Q Exactive Orbitrap Plus to identify the peptides from E-Jiao. We also used the QE Plus to investigate the E-Jiao peptides in rat blood.
ORGANISM(S): Equus caballus (Horse) 
2024-07-03 | PXD052456 | Pride
E-jiao  q exactive orbitrap plus Donkey hide gelatin 
TranscriptomicsIdentification of novel tissue-specific transcription arising from E-cadherin/CDH1 intron2: a novel protein isoform increases gastric cancer cell invasion and angiogenesis.
E-cadherin, a protein encoded by the CDH1 gene is the dominant epithelial cell adhesion molecule playing a crucial role in epithelial tissue polarity and structural integrity. The progression of 90% or more carcinomas is believed to be mediated by disruption of normal E-cadherin expression, subcellu...
ORGANISM(S): Homo sapiens 
2012-08-01 | E-GEOD-32540 | biostudies-arrayexpress
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