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MetabolomicsDynamic utilization of low-molecular-weight organic substrates across a microbial growth rate gradient

AIM: Low-molecular-weight organic substances (LMWOSs) are at the nexus between micro-organisms, plant roots, detritus and the soil mineral matrix. The nominal oxidation state of carbon (NOSC) has been suggested as a potential parameter for modelling microbial uptake rates of LMWO...

2023-08-14 | MTBLS3558 | MetaboLights
MetabolomicsAn alkaline-extracted low-molecular-weight heteroglucan from Ganoderma lucidum enhances immunity by modulating the gut microbiota

Ganoderma lucidum polysaccharides exhibit various biological activities, but conventional extraction is biased toward high-molecular-weight polymers. This study aimed to explore the structure and bioactivity of low-molecular-weight polysaccharides from Ganoderma lucidum...

2026-06-18 | MTBLS14649 | MetaboLights
MetabolomicsOral administration of low-molecular-weight heparin ameliorates colitis by enhancing the gut mucus barrier via microbial tryptophan metabolites

Background and Purpose: Previous studies have reported that oral low molecular weight heparin (LMWH) ameliorated colitis by undefined mechanisms in ulcerative colitis (UC) patients. Our study explored the mechanisms of LMWH on colitis from the perspective of gut microbiota and its metabolites.

2025-10-12 | MTBLS5770 | MetaboLights
MetabolomicsEarly Mechanistic Events Induced by Secondhand Smoke Prevalent Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells
Not available
ORGANISM(S): Mus musculus 
ST001124 | MetabolomicsWorkbench
MetabolomicsEarly Mechanistic Events Induced by Secondhand Smoke Prevalent Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells (part-I)
Not available
ORGANISM(S): Mus musculus 
ST001094 | MetabolomicsWorkbench
MetabolomicsIntegrated analysis of transcriptome and metabolome reveals molecular responses to ammonia stress in the gills of Litopenaeus vannamei under low-salinity conditions

High ammonia nitrogen stress significantly compromises the survival of Litopenaeus vannamei under low-salinity conditions, posing a common challenge in low-salinity aquaculture. However, existing studies predominantly focus on ammonia nitrogen responses unde...

2026-04-10 | MTBLS14054 | MetaboLights
TranscriptomicsGenome-Wide Expression Profiles in Very Low Birth Weight Infants With Neonatal Sepsis
Bacterial sepsis is associated with high morbidity and mortality in preterm infants. However, diagnosis of sepsis and identification of the causative agent remains challenging. Our aim was to determine genome-wide expression profiles of very low birth weight (VLBW) infants with and without bacterial...
ORGANISM(S): Homo sapiens 
2016-05-29 | E-MTAB-4785 | biostudies-arrayexpress
MetabolomicsA low protein diet drives short and long-term improvements in metabolic health in a mouse model of sleeve gastrectomy

Despite the largely beneficial impact of bariatric surgery on obesity and metabolic disease, many patients continue to suffer from obesity after surgery and weight recurrence is common. The success of bariatric surgery may be impacted by diet. While bariatric surgery guidelines recommend a high-p...

2025-10-13 | MTBLS13046 | MetaboLights
ProteomicsAge-related cleavages of crystallins in human lens cortical fibre cells generate a plethora of low molecular weight peptides and cross-linked crystallin complexes
A large variety of low molecular weight (LMW) peptides, derived from the breakdown of crystallins, have been reported in middle to old age human lenses. The proliferation of these LMW peptides coincides with the earliest stages of cataract formation, suggesting that the protein cleavages involved ma...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081536 | MassIVE
ProteomicsA sub-optimal protein precipitation method to improve identification of low molecular weight less abundant proteins
Mass spectrometry-based proteomics studies have enabled identification and quantification of thousands of proteins from biological samples. High molecular weight abundant proteins are readily sampled in global proteomics studies compared to low molecular weight less abundant proteins. Although exten...
ORGANISM(S): Homo sapiens (Human) 
2021-08-19 | PXD023648 | Pride
Small protein Serum Low molecular weight protein Breast cacner cell line Tumour Protein precipitation 
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