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OtherThe E3 ubiquitin ligase LTN1 downregulates RNF10 level and uS3 ubiquitination
During gene expression, ribosome stalling frequently occurs and can lead to detrimental effects on cellular homeostasis. Several quality control mechanisms, including RQC and NRD, have been identified to resolve these aberrant translation events. While the molecular mechanisms of each pathway have b...
ORGANISM(S): Mus musculus 
2025-10-25 | GSE303675 | GEO
UnknownSingle-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase.
Not available
S-EPMC3562785 | biostudies-literature
UnknownUbiquitylation by the Ltn1 E3 ligase protects 60S ribosomes from starvation-induced selective autophagy.
Not available
S-EPMC3998797 | biostudies-literature
UnknownStructure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunits.
Not available
S-EPMC4961192 | biostudies-literature
UnknownLTN1 promotes RLR degradation to inhibit immune response to RNA virus through the ESCRT pathway.
Not available
S-EPMC11210911 | biostudies-literature
UnknownRqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits.
Not available
S-EPMC4933273 | biostudies-literature
Genomics
Crosstalk between the ribosome quality control-associated E3 ubiquitin ligases LTN1 and RNF10
PRJNA1295581 | ENA
ProteomicsLipid mediated–phase separation of AGO proteins on the ER controls nascent peptide ubiquitination
we sought to determine whether dmAGO1 and Ltn1 share common ubiquitinated nascent peptide targets. For this purpose, we performed the UBA bead-based immunoprecipitation followed by mass spec experiments to identify the ubiquitinated nascent peptide targets of dmAGO1 and Ltn1, respectively. In this a...
ORGANISM(S): Drosophila Melanogaster 
2022-02-18 | PXD031749 |
UnknownIntrogression of the bread wheat D genome encoded Lr34/Yr18/Sr57/Pm38/Ltn1 adult plant resistance gene into Triticum turgidum (durum wheat).
Not available
S-EPMC10581953 | biostudies-literature
TranscriptomicsDysregulation of ribosome-associated quality control elicits cognitive disorders via overaccumulation of TTC3
To investigate overaccumulated TTC3 inhibits translation initiation in Ltn1 KO neurons, we established harringtonine treated WT and Ltn1 KO mice primary cultured cortical neurons with Ttc3 RNAi or scrambled RNAi. We then performed read (footprint) count analysis at translation initiation site using ...
ORGANISM(S): Mus musculus 
2024-02-12 | GSE228437 | GEO
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