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MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
ProteomicsIdentification of proteins differentially regulated by indisulam in AGS cells using label-free quantitative proteomics
In this project, we used label-free quantitative proteomics to identify proteins that are differentially regulated by indisulam in the gastric cancer AGS cell line.
ORGANISM(S): Homo Sapiens 
2022-09-17 | PXD036835 |
ProteomicsIdentification of the Voltage Dependent Anion Channel (VDAC1) protein implicated in the pathology of Hepatocellular carcinoma (HCC) by quantitative proteomics and integrating genetic analysis
Hepatocellular carcinoma (HCC) is a heterogeneous tumor associated with multiple signaling pathway alterations, among which mitochondrial dysfunction has been found to play an important role.
ORGANISM(S): Homo Sapiens 
2020-01-12 | PXD017072 |
TranscriptomicsRegulation of Angiogenesis by EZH2
While VEGF-targeted therapies are showing promise in clinical studies, new angiogenesis targets are needed to make additional gains. Here, we show that increased Zeste homologue 2 (EZH2) expression in either tumor cells or in tumor vasculature is predictive of poor clinical outcome. The increase in ...
ORGANISM(S): Homo sapiens 
2010-10-12 | E-GEOD-20381 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing of Ovis aries
We have completed the high quality reference genome for domestic sheep (Oar v3.1) and performed a detailed survey of gene expression across different tissues. RNA-seq data of 7 tissue types from the reference female Texel and skin tissue from a Gansu alpine fine wool sheep were sequenced. Here is t...
ORGANISM(S): Ovis aries 
2014-06-06 | E-GEOD-56643 | biostudies-arrayexpress
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