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MetabolomicsComparative metabolomics reveals serum metabolites changes in goats during different developmental stages

Goats can provide meat, milk and skins for humans and are livestock with high economic benefits. However, despite their economic significance, the comprehensive analysis of goats' serum metabolic profile and its intricate alterations throughout their developmental journey remains conspicuously ab...

2024-06-04 | MTBLS8944 | MetaboLights
UnknownMechanistic evaluation of Jiu Wei Qing Zhi Gao in non-alcoholic fatty liver disease: insights from network Pharmacology and experimental validation.
Not available
S-EPMC11992867 | biostudies-literature
TranscriptomicsmicroRNA-1 negatively regulates expression of the hypertrophy-associated genes calmodulin and Mef2a
Calcium signaling is a central regulator of cardiomyocyte growth and function. Calmodulin is a critical mediator of calcium signals. Because the amount of calmodulin within cardiomyocytes is limiting, precise regulation of calmodulin expression may be an important for regulation of calcium signaling...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-13874 | biostudies-arrayexpress
TranscriptomicsDual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system
This SuperSeries is composed of the following subset Series: GSE40506: Genome-wide mapping of Olig2 targets in primary oligodendrocytes GSE40510: Expression data from Sip1 cKO and control mice spinal cord Refer to individual Series
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-40431 | biostudies-arrayexpress
GenomicsGenome-wide mapping of Olig2 targets in primary oligodendrocytes
Myelination by oligodendrocytes in the central nervous system (CNS) is essential for proper brain function, yet the molecular determinants that control this process remain poorly understood. The basic helix-loop-helix transcription factors Olig1 and Olig2 promote myelination, whereas bone morphogene...
ORGANISM(S): Rattus norvegicus 
2012-08-31 | E-GEOD-40506 | biostudies-arrayexpress
TranscriptomicsExpression data from Sip1 cKO and control mice spinal cord
Myelination by oligodendrocytes in the central nervous system (CNS) is essential for proper brain function, yet the molecular determinants that control this process remain poorly understood. The basic helix-loop-helix transcription factors Olig1 and Olig2 promote myelination, whereas bone morphogene...
ORGANISM(S): Mus musculus 
2012-08-31 | E-GEOD-40510 | biostudies-arrayexpress
TranscriptomicsActivation of the chromatin-remodeling factor Smarca4/Brg1 cooperates with Olig2 to establish oligodendrocyte identity and control CNS myelination [RNA-seq]
Spinal cord mRNA profiles of 14-day-old control (Brg1c/+;Olig1-Cre) and Smarca4/Brg1 conditional knockout (Brg1c/c;Olig1-Cre) mice were generated by RNA-seq. Differential expressed genes are identified using Cuffdiff and validated with qPCR. Spinal cord mRNA profiles of 14-day old control and Brg1c/...
ORGANISM(S): Mus musculus 
2013-01-20 | E-GEOD-42443 | biostudies-arrayexpress
UnknownInfluence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study.
Not available
S-EPMC8004025 | biostudies-literature
UnknownHydrogen bond based smart polymer for highly selective and tunable capture of multiply phosphorylated peptides.
Not available
S-EPMC5587758 | biostudies-literature
TranscriptomicsKnockout PTTG1 HCT116 cells
To identify potential PTTG1-targeted genes, total RNA from PTTG1+/+ and PTTG1-/- HCT 116 cells was isolated using the RNeasy Kit (Qiagen) and analyzed using Illumina microarrays (HumanHT-12_V4). Raw data were processed according to the manufacturerâ??s standard procedure and further analyzed using ...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-58863 | biostudies-arrayexpress
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