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GenomicsLoss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
PRJNA663333 | ENA
UnknownCRISPR/Cas9 genome-wide screening identifies LUC7L2 that promotes radioresistance via autophagy in nasopharyngeal carcinoma cells.
Not available
S-EPMC8671510 | biostudies-literature
UnknownLoss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.
Not available
S-EPMC8314041 | biostudies-literature
TranscriptomicsLoss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
Oxidative phosphorylation (OXPHOS) and glycolysis are the two major pathways for ATP production. The reliance on each varies across tissues and cell states, and can influence susceptibility to disease. At present, the full set ofmolecular mechanisms governing the relative expression and balance of t...
ORGANISM(S): Homo sapiens 
2021-04-13 | GSE157917 | GEO
TranscriptomicsLUC7 proteins define two major classes of 5' splice sites in animals and plants
Mutation or deletion of the U1 snRNP-associated factor LUC7L2 is associated with myeloid neoplasms, and knockout of LUC7L2 alters cellular metabolism. Here, we uncover that members of the LUC7 protein family differentially regulate two major classes of 5' splice sites (5'SS) and broadly regulate mRN...
ORGANISM(S): Homo sapiens Arabidopsis thaliana 
2024-12-30 | GSE285019 | GEO
ProteomicsProteome remodeling in LUC7L2-depleted and galactose-grown cells
Study of the proteome of K562 LUC7L2WT and LUC7L2KO cells grown for 14 days in DMEM media containing either 25mM glucose or 25mM galactose.
ORGANISM(S): Homo sapiens (Human) 
2021-04-12 | PXD021917 | Pride
Luc7l2 splicing glucose galactose metabolism mitochondria 
UnknownLUC7 proteins define two major classes of 5' splice sites in animals and plants.
Not available
S-EPMC11842720 | biostudies-literature
UnknownFunctional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms.
Not available
S-EPMC8078730 | biostudies-literature
UnknownPutative RNA-splicing gene LUC7L2 on 7q34 represents a candidate gene in pathogenesis of myeloid malignancies.
Not available
S-EPMC3674458 | biostudies-literature
UnknownFunctional Analysis of the Zinc Finger Modules of the S. cerevisiae Splicing Factor Luc7.
Not available
S-EPMC10862913 | biostudies-literature
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