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TranscriptomicsOlive oil phenols and miRNA in the aging mouse brain
The aim of this study was to evaluate the effects of olive oil phenols on brain aging in mice, focusing on changes in the microRNA profile. A sister experiment focusing on gene expression changes is also submitted to ArrayExpress under accession number E-MTAB-1530 ( http://www.ebi.ac.uk/arrayexpre...
ORGANISM(S): Mus musculus 
2013-09-10 | E-MTAB-1549 | biostudies-arrayexpress
TranscriptomicsOlive oil phenols and GE in the aging mouse brain
The aim of this study was to evaluate whether the dietary treatment with olive oil phenols modifies the profile of microRNA and gene expression in different areas of the aging mouse brain and to correlate these changes with the cognitive and motor changes observed in the same aging animals. C57Bl/...
ORGANISM(S): Mus musculus 
2013-09-10 | E-MTAB-1530 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of colon mucosa after cytotoxic insult in wild type and Apc-mutated rats: possible relation with resistance to apoptosis during carcinogenesis
Gene expression profiles of the colon mucosa of wild type and PIRC rats after 1,2-dimethylhydrazine (DMH)-treatment
ORGANISM(S): Rattus norvegicus 
2016-11-03 | E-MTAB-4910 | biostudies-arrayexpress
TranscriptomicsCharacterization of HCT8 clones with MDR phenotype.
We selected and characterized doxorubicin/5FU resistant HCT-8/R clones from sensitive parental cells, analyzing several parameters: cell cycle phase distribution, apoptotic activity, expression, distribution and functionality of the P-gp efflux pump, ultrastructural features, invasiveness and transc...
ORGANISM(S): Homo sapiens 
2016-02-29 | E-MTAB-3780 | biostudies-arrayexpress
TranscriptomicsBUTYRATE ENEMAS ON PATIENTS WITH ENTEROSTOMY
The aim of this study was to evaluate the effects of sodium butyrate enemas on the mucosal genes expression profiles of patients with an enterostomy.
ORGANISM(S): Homo sapiens 
2015-09-01 | E-MTAB-2436 | biostudies-arrayexpress
TranscriptomicsAcute rapamycin rescues the hyperexcitable phenotype of accumbal medium spiny neurons in the valproic acid rat model of autism spectrum disorder
The aim of the study was to investigate the involvement of the mTOR pathway in the autism spectrum disorder. Adolescent male rats, prenatally exposed to valproic acid (500 mg/kg ip on gestational day 12.5), were treated with the mTOR inhibitor rapamycin (10 mg/kg, ip, two consecutive days starting a...
ORGANISM(S): Rattus norvegicus 
2022-09-06 | E-MTAB-12056 | biostudies-arrayexpress
TranscriptomicsAnti-CGRP Monoclonal Antibodies Counteract Interoceptive Awareness of Malaise
Study of the expression profiles of brain regions (amygdala, hippocampus and cerebral cortex) and trigeminal ganglia collected from rats treated with fremanezumab, an anti-calcitonin gene related peptide (CGRP) mAb, used for the prevention of migraine.
ORGANISM(S): Rattus norvegicus 
2024-05-30 | E-MTAB-13507 | biostudies-arrayexpress
TranscriptomicsGene expression and survival in patients with colorectal cancer
The aim of the study was to elucidate the association between copy number alterations and gene expression profiles in colorectal cancer patients and to identify molecular signatures that are associated with survival.
ORGANISM(S): Homo sapiens 
2016-05-25 | E-MTAB-4353 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of lymphocytes form post-menopausal women after consuming de-alcoholized red wine with low or high proanthocyanidin concentrations
Experiment with 32 hybridizations, using 16 samples of species [Homo sapiens], using 32 arrays of array design [Affymetrix Custom Array - NuGO_Hs1a520180], producing 32 raw data files and 1 transformed and/or normalized data files.
ORGANISM(S): Homo sapiens 
2010-07-20 | E-MEXP-2616 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat colon tumors induced by DMH
344 rats were treated twice, one week apart, with subcutaneous injections of 1,2-dimethylhydrazine (150 mg/kg x 2). Thirty-two weeks after the first DMH injection, rats were sacrificed and colonic tumours (T) and normal colon mucosa (NM) harvested and stored in RNAlater. Genomic DNA was extracted f...
ORGANISM(S): Rattus norvegicus 
2010-07-20 | E-MEXP-2487 | biostudies-arrayexpress
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