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TranscriptomicsmRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer
The intention was to detect genes that are determining trastuzumab efficiency in HER2-positive breast cancer cell lines with different resistance phenotypes. While BT474 should be sensitive to the drug treatment, HCC1954 is expected to be resistant due to a PI3K mutation. The cell line BTR50 has bee...
ORGANISM(S): Homo sapiens 
2015-04-21 | E-GEOD-55005 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA sequencing of small intestinal dendritic cells from C57BL/6, RORgt-/- and RORgt-Cre x Ltb-flox mice
Cryptopatches (CP) and isolated lymphoid follicles (ILF) are evolutionary ancient lymphoid structures found in the intestines of all vertebrates. These structures are demarcated by a poorly characterised subset of mononuclear phagocytes (MPh), called CP/ILF-associated (CIA)-MPh. We could demonstrat...
ORGANISM(S): Mus musculus 
2020-11-24 | E-MTAB-9522 | biostudies-arrayexpress
TranscriptomicsRNA-seq of small intestinal macrophages, neutrophils, CD103-CD11b+cDC and cryptopatch and ILF associated mononuclear phagocytes (CIA-MPh)
Cryptopatches (CP) and isolated lymphoid follicles (ILF) are evolutionary ancient lymphoid structures found in the intestines of all vertebrates. These structures are demarcated by a poorly characterised subset of mononuclear phagocytes (MPh), called CP/ILF-associated (CIA)-MPh. CIA-MPh expressed v...
ORGANISM(S): Mus musculus 
2020-11-24 | E-MTAB-9505 | biostudies-arrayexpress
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