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TranscriptomicsmRNA expression after siRNA-mediated knock down of Enhancer of zeste homolog 2 (Ezh2) in human umbilical vein endothelial cells
mRNA expression after Ezh2 knock down was analyzed to identify genes regulated by Ezh2. Human umbilical vein endothelial cells (HUVEC) were transfected with 25 nmol/L of control small interfering RNA (siRNA) (Silencer Select Negative Control Ambion, Austin, TX) or siRNA directed against Ezh2 (s4918;...
ORGANISM(S): Homo sapiens 
2012-10-16 | E-GEOD-41610 | biostudies-arrayexpress
TranscriptomicsAttenuation of early atherogenesis in LDLR-KO mice by proteasome inhibition
To get further insights into the processes leading to attenuation of early stage atherosclerosis in the bortezomib treated LDLR-KO mice, microarray profiling of gene expression was performed on RNA taken from whole aortae of bortezomib treated LDLR-KO and sham- treated LDLR-KO mice fed a Western die...
ORGANISM(S): Mus musculus 
2011-07-13 | E-GEOD-30638 | biostudies-arrayexpress
ProteomicsMulti-omics profiling of Müller cells in diabetic retinopathy identifies the glucocorticoid receptor as a master regulator of gliotic response
Diabetic retinopathy (DR), the leading cause of blindness in working-age adults, is thought to be primarily a microvascular complication of diabetes. As a central element of the retinal neurovascular unit, Müller cells, the major macroglia of the retina, are important for maintaining a healthy and f...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-23 | PXD045085 | Pride
Diabetic retinopathy Proteomic analysis Expression profiling Müller glia Mrna 
UnknownIntegrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers
Not available
S-SCDT-EMM-2020-12871 | biostudies-other
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